Literature DB >> 17021062

Rapid screening of topoisomerase gene mutations by a novel melting curve analysis method for early warning of fluoroquinolone-resistant Streptococcus pneumoniae emergence.

Kazuko Y Fukushima1, Yoichi Hirakata, Kazuyuki Sugahara, Katsunori Yanagihara, Akira Kondo, Shigeru Kohno, Shimeru Kamihira.   

Abstract

We developed a real-time PCR assay combined with melting curve analysis for rapidly genotyping quinolone resistance-determining regions (QRDR) of topoisomerase genes in Streptococcus pneumoniae. This assay was not only accurate for the screening of fluoroquinolone (FQ) resistance but also relevant as an early warning system for detecting preexisting single QRDR mutations.

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Year:  2006        PMID： 17021062      PMCID： PMC1698396          DOI： 10.1128/JCM.01887-06

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  27 in total

1.  Investigation of the susceptibility trends in Japan to fluoroquinolones and other antimicrobial agents in a nationwide collection of clinical isolates: a longitudinal analysis from 1994 to 2002.

Authors:  Keizo Yamaguchi; Akira Ohno
Journal:  Diagn Microbiol Infect Dis       Date:  2005-06       Impact factor: 2.803

2.  Rapid detection of a chromosomally mediated penicillin resistance-associated ponA mutation in Neisseria gonorrhoeae using a real-time PCR assay.

Authors:  Frédérique Vernel-Pauillac; Virginie Falcot; David Whiley; Fabrice Merien
Journal:  FEMS Microbiol Lett       Date:  2006-02       Impact factor: 2.742

3.  Real-time PCR screening for 16S rRNA mutations associated with resistance to tetracycline in Helicobacter pylori.

Authors:  Erik Glocker; Marco Berning; Monique M Gerrits; Johannes G Kusters; Manfred Kist
Journal:  Antimicrob Agents Chemother       Date:  2005-08       Impact factor: 5.191

4.  Detection of mutations associated with macrolide resistance in thermophilic Campylobacter spp. by real-time PCR.

Authors:  Sylvie Vacher; Armelle Menard; Elisabeth Bernard; Adriana Santos; Francis Megraud
Journal:  Microb Drug Resist       Date:  2005       Impact factor: 3.431

5.  Optochin revisited: defining the optimal type of blood agar for presumptive identification of Streptococcus pneumoniae.

Authors:  M A Gardam; M A Miller
Journal:  J Clin Microbiol       Date:  1998-03       Impact factor: 5.948

6.  Contribution of mutations in gyrA and parC genes to fluoroquinolone resistance of mutants of Streptococcus pneumoniae obtained in vivo and in vitro.

Authors:  J Tankovic; B Perichon; J Duval; P Courvalin
Journal:  Antimicrob Agents Chemother       Date:  1996-11       Impact factor: 5.191

7.  Fluoroquinolone-resistant Streptococcus pneumoniae strains occur frequently in elderly patients in Japan.

Authors:  Shin-Ichi Yokota; Kiyoshi Sato; Osamu Kuwahara; Satoshi Habadera; Naoyuki Tsukamoto; Hironori Ohuchi; Hirotsugu Akizawa; Tetsuo Himi; Nobuhiro Fujii
Journal:  Antimicrob Agents Chemother       Date:  2002-10       Impact factor: 5.191

8.  [Molecular epidemiology of fluoroquinolone-resistant Streptococcus pneumoniae in Japan].

Authors:  Shin-ichi Yokota; Kiyoshi Sato; Shigeru Yoshida; Nobuhiro Fujii
Journal:  Kansenshogaku Zasshi       Date:  2004-05

9.  PCR-oligonucleotide ligation assay for detection of point mutations associated with quinolone resistance in Streptococcus pneumoniae.

Authors:  Mai-Ha Bui; Gregory G Stone; Angela M Nilius; Laurel Almer; Robert K Flamm
Journal:  Antimicrob Agents Chemother       Date:  2003-04       Impact factor: 5.191

10.  Antimicrobial susceptibility breakpoints and first-step parC mutations in Streptococcus pneumoniae: redefining fluoroquinolone resistance.

Authors:  Sue Lim; Darrin Bast; Allison McGeer; Joyce de Azavedo; Donald E Low
Journal:  Emerg Infect Dis       Date:  2003-07       Impact factor: 6.883
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  7 in total

1.  Development and evaluation of a novel single-nucleotide-polymorphism real-time PCR assay for rapid detection of fluoroquinolone-resistant Mycoplasma bovis.

Authors:  M Ben Shabat; I Mikula; I Gerchman; I Lysnyansky
Journal:  J Clin Microbiol       Date:  2010-06-09       Impact factor: 5.948

2.  Evaluation of melting curve analysis for screening the most prevalent mutations in topoisomerase genes from Streptococcus pneumoniae.

Authors:  Roberto G Melano; Rachel Higgins; Christine Seah; Steven J Drews
Journal:  J Clin Microbiol       Date:  2008-01       Impact factor: 5.948

3.  Real-time PCR detection of gyrA and parC mutations in Streptococcus pneumoniae.

Authors:  S Page; F Vernel-Pauillac; O O'Connor; S Bremont; F Charavay; P Courvalin; C Goarant; S Le Hello
Journal:  Antimicrob Agents Chemother       Date:  2008-08-25       Impact factor: 5.191

4.  Melting curve analysis for rapid detection of topoisomerase gene mutations in Haemophilus influenzae.

Authors:  Shigeki Nakamura; Katsunori Yanagihara; Yoshitomo Morinaga; Koichi Izumikawa; Masafumi Seki; Hiroshi Kakeya; Yoshihiro Yamamoto; Shimeru Kamihira; Shigeru Kohno
Journal:  J Clin Microbiol       Date:  2009-01-07       Impact factor: 5.948

5.  In Vitro Activity of Lascufloxacin against Streptococcus pneumoniae with Mutations in the Quinolone Resistance-Determining Regions.

Authors:  Mika Murata; Kosuke Kosai; Shunsuke Yamauchi; Daisuke Sasaki; Norihito Kaku; Naoki Uno; Yoshitomo Morinaga; Hiroo Hasegawa; Taiga Miyazaki; Koichi Izumikawa; Hiroshi Mukae; Katsunori Yanagihara
Journal:  Antimicrob Agents Chemother       Date:  2018-03-27       Impact factor: 5.191

6.  In vitro activity of garenoxacin against Streptococcus pneumoniae mutants with characterized resistance mechanisms.

Authors:  Kazuko Yamamoto; Katsunori Yanagihara; Kazuyuki Sugahara; Yoshifumi Imamura; Masafumi Seki; Koichi Izumikawa; Hiroshi Kakeya; Yoshihiro Yamamoto; Yoichi Hirakata; Shimeru Kamihira; Shigeru Kohno
Journal:  Antimicrob Agents Chemother       Date:  2009-05-18       Impact factor: 5.191

7.  Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone resistance-determining regions.

Authors:  Yoichi Hirakata; Kaori Ohmori; Miwako Mikuriya; Takeshi Saika; Kaoru Matsuzaki; Miyuki Hasegawa; Masumitsu Hatta; Natsuo Yamamoto; Hiroyuki Kunishima; Hisakazu Yano; Miho Kitagawa; Kazuaki Arai; Kazuyoshi Kawakami; Intetsu Kobayashi; Ronald N Jones; Shigeru Kohno; Keizo Yamaguchi; Mitsuo Kaku
Journal:  Antimicrob Agents Chemother       Date:  2009-08-03       Impact factor: 5.191
  7 in total

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