Literature DB >> 16569894

New real-time PCR assay using locked nucleic acid probes to assess prevalence of ParC mutations in fluoroquinolone-susceptible Streptococcus pneumoniae isolates from France.

Jean-Winoc Decousser1, Imen Methlouthi, Patrick Pina, Anne Collignon, Pierre Allouch.   

Abstract

A real-time PCR assay with locked nucleic acid probes was developed to screen mutations at codons 79 and 83 of the Streptococcus pneumoniae parC gene. Only silent mutations were detected among 236 French invasive fluoroquinolone-susceptible strains. This test could be useful for some high-risk patients or in national surveys.

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Year:  2006        PMID： 16569894      PMCID： PMC1426917          DOI： 10.1128/AAC.50.4.1594-1598.2006

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  26 in total

1.  Evaluation of susceptibility testing to detect fluoroquinolone resistance mechanisms in Streptococcus pneumoniae.

Authors:  D C Richardson; D Bast; A McGeer; D E Low
Journal:  Antimicrob Agents Chemother       Date:  2001-06       Impact factor: 5.191

Review 2.  PNA and LNA throw light on DNA.

Authors:  Vadim V Demidov
Journal:  Trends Biotechnol       Date:  2003-01       Impact factor: 19.536

3.  In vitro activity of moxifloxacin against recent community-acquired respiratory tract pathogens isolated in France: a national survey.

Authors:  J W Decousser; P-Y Allouch; P Courvalin; R Leclercq
Journal:  Int J Antimicrob Agents       Date:  2002-09       Impact factor: 5.283

Review 4.  A review of Streptococcus pneumoniae infection treatment failures associated with fluoroquinolone resistance.

Authors:  Jeffrey D Fuller; Donald E Low
Journal:  Clin Infect Dis       Date:  2005-05-26       Impact factor: 9.079

5.  Fluoroquinolone resistance in Streptococcus pneumoniae in United States since 1994-1995.

Authors:  Angela B Brueggemann; Stacy L Coffman; Paul Rhomberg; Holly Huynh; Laurel Almer; Angela Nilius; Robert Flamm; Gary V Doern
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

6.  Accumulation of 10 fluoroquinolones by wild-type or efflux mutant Streptococcus pneumoniae.

Authors:  Laura J V Piddock; M M Johnson
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

7.  Fluoroquinolone-resistant Streptococcus pneumoniae strains occur frequently in elderly patients in Japan.

Authors:  Shin-Ichi Yokota; Kiyoshi Sato; Osamu Kuwahara; Satoshi Habadera; Naoyuki Tsukamoto; Hironori Ohuchi; Hirotsugu Akizawa; Tetsuo Himi; Nobuhiro Fujii
Journal:  Antimicrob Agents Chemother       Date:  2002-10       Impact factor: 5.191

8.  Efficacy and pharmacodynamics of simulated human-like treatment with levofloxacin on experimental pneumonia induced with penicillin-resistant pneumococci with various susceptibilities to fluoroquinolones.

Authors:  Delphine Croisier; Pascal Chavanet; Catherine Lequeu; Abderrahmane Ahanou; Anne Nierlich; Catherine Neuwirth; Lionel Piroth; Michel Duong; Marielle Buisson; Henri Portier
Journal:  J Antimicrob Chemother       Date:  2002-09       Impact factor: 5.790

9.  Frequency of isolation and antimicrobial susceptibility of bacterial pathogens isolated from patients with bloodstream infections: a French prospective national survey.

Authors:  J-W Decousser; P Pina; F Picot; C Delalande; B Pangon; P Courvalin; P Allouch
Journal:  J Antimicrob Chemother       Date:  2003-04-14       Impact factor: 5.790

10.  PCR-oligonucleotide ligation assay for detection of point mutations associated with quinolone resistance in Streptococcus pneumoniae.

Authors:  Mai-Ha Bui; Gregory G Stone; Angela M Nilius; Laurel Almer; Robert K Flamm
Journal:  Antimicrob Agents Chemother       Date:  2003-04       Impact factor: 5.191
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  1 in total

1.  Real-time PCR detection of gyrA and parC mutations in Streptococcus pneumoniae.

Authors:  S Page; F Vernel-Pauillac; O O'Connor; S Bremont; F Charavay; P Courvalin; C Goarant; S Le Hello
Journal:  Antimicrob Agents Chemother       Date:  2008-08-25       Impact factor: 5.191
  1 in total

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