Literature DB >> 18710960

Calcified plaque: measurement of area at thin-section flat-panel CT and 64-section multidetector CT and comparison with histopathologic findings.

Ammar Sarwar1, Johannes Rieber, Eline A Q Mooyaart, Sujith K Seneviratne, Stuart L Houser, Fabian Bamberg, O Christopher Raffel, Rajiv Gupta, Mannudeep K Kalra, Homer Pien, Hang Lee, Thomas J Brady, Udo Hoffmann.   

Abstract

The purpose of this study was to assess the blooming artifacts in ex vivo coronary arteries at multidetector computed tomography (CT) and flat-panel-volume CT by comparing measured areas of calcified plaque with respect to the reference standard of histopathologic findings. Three ex vivo hearts were scanned with multidetector CT and flat-panel-volume CT after institutional review board approval. The area of calcified plaque was measured at histopathologic examination, multidetector CT, and flat-panel-volume CT. The plaque area was overestimated at multidetector CT by 400% (4.61/1.15) on average, and the predicted difference between the measurements was significant (3.46 mm(2), P = .018). The average overestimation of plaque area at flat-panel-volume CT was twofold (214% [2.18/1.02]), and the predicted difference was smaller (1.16 mm(2), P = .08). The extent of the blooming artifact in visualizing calcified coronary plaque is reduced by using flat-panel-volume CT. (c) RSNA, 2008.

Mesh:

Year:  2008        PMID: 18710960     DOI: 10.1148/radiol.2483072003

Source DB:  PubMed          Journal:  Radiology        ISSN: 0033-8419            Impact factor:   11.105


  23 in total

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