| Literature DB >> 25068026 |
Gitsios Gitsioudis1, Hugo A Katus1, Grigorios Korosoglou1.
Abstract
Chronic inflammatory mechanisms in the arterial wall lead to atherosclerosis, and include endothelial cell damage, inflammation, apoptosis, lipoprotein deposition, calcification and fibrosis. Cardiac computed tomography angiography (CCTA) has been shown to be a promising tool for non-invasive assessment of theses specific compositional and structural changes in coronary arteries. This review focuses on the technical background of CCTA-based quantitative plaque characterization. Furthermore, we discuss the available evidence for CCTA-based plaque characterization and the potential role of CCTA for risk stratification of patients with coronary artery disease.Entities:
Keywords: Atherosclerotic plaque composition; Biomarkers; Multi-slice cardiac computed tomography; Quantification analysis
Year: 2014 PMID: 25068026 PMCID: PMC4110614 DOI: 10.4330/wjc.v6.i7.663
Source DB: PubMed Journal: World J Cardiol