Literature DB >> 18682554

Vitamin C and cancer revisited.

Balz Frei1, Stephen Lawson.   

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Year:  2008        PMID: 18682554      PMCID: PMC2516245          DOI: 10.1073/pnas.0806433105

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


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  19 in total

1.  The orthomolecular treatment of cancer. II. Clinical trial of high-dose ascorbic acid supplements in advanced human cancer.

Authors:  E Cameron; A Campbell
Journal:  Chem Biol Interact       Date:  1974-10       Impact factor: 5.192

Review 2.  Ascorbic acid and the glycosaminoglycans. An orthomolecular approach to cancer and other diseases.

Authors:  E Cameron; L Pauling
Journal:  Oncology       Date:  1973       Impact factor: 2.935

Review 3.  The broad spectrum of responses to oxidants in proliferating cells: a new paradigm for oxidative stress.

Authors:  K J Davies
Journal:  IUBMB Life       Date:  1999-07       Impact factor: 3.885

4.  Enhancement of antitumor activity of ascorbate against Ehrlich ascites tumor cells by the copper:glycylglycylhistidine complex.

Authors:  E Kimoto; H Tanaka; J Gyotoku; F Morishige; L Pauling
Journal:  Cancer Res       Date:  1983-02       Impact factor: 12.701

5.  Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer. A controlled trial.

Authors:  E T Creagan; C G Moertel; J R O'Fallon; A J Schutt; M J O'Connell; J Rubin; S Frytak
Journal:  N Engl J Med       Date:  1979-09-27       Impact factor: 91.245

6.  Phase I clinical trial of i.v. ascorbic acid in advanced malignancy.

Authors:  L J Hoffer; M Levine; S Assouline; D Melnychuk; S J Padayatty; K Rosadiuk; C Rousseau; L Robitaille; W H Miller
Journal:  Ann Oncol       Date:  2008-06-09       Impact factor: 32.976

7.  Supplemental ascorbate in the supportive treatment of cancer: reevaluation of prolongation of survival times in terminal human cancer.

Authors:  E Cameron; L Pauling
Journal:  Proc Natl Acad Sci U S A       Date:  1978-09       Impact factor: 11.205

8.  Vitamin C pharmacokinetics: implications for oral and intravenous use.

Authors:  Sebastian J Padayatty; He Sun; Yaohui Wang; Hugh D Riordan; Stephen M Hewitt; Arie Katz; Robert A Wesley; Mark Levine
Journal:  Ann Intern Med       Date:  2004-04-06       Impact factor: 25.391

9.  Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer.

Authors:  E Cameron; L Pauling
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205

10.  High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy. A randomized double-blind comparison.

Authors:  C G Moertel; T R Fleming; E T Creagan; J Rubin; M J O'Connell; M M Ames
Journal:  N Engl J Med       Date:  1985-01-17       Impact factor: 91.245

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  37 in total

Review 1.  Ascorbic acid: chemistry, biology and the treatment of cancer.

Authors:  Juan Du; Joseph J Cullen; Garry R Buettner
Journal:  Biochim Biophys Acta       Date:  2012-06-20

2.  Fluorine-18-Labeled Thymidine Positron Emission Tomography (FLT-PET) as an Index of Cell Proliferation after Pharmacological Ascorbate-Based Therapy.

Authors:  John A Cieslak; Zita A Sibenaller; Susan A Walsh; Laura L Boles Ponto; Juan Du; John J Sunderland; Joseph J Cullen
Journal:  Radiat Res       Date:  2015-12-31       Impact factor: 2.841

3.  Manganoporphyrins and ascorbate enhance gemcitabine cytotoxicity in pancreatic cancer.

Authors:  John A Cieslak; Robert K Strother; Malvika Rawal; Juan Du; Claire M Doskey; Samuel R Schroeder; Anna Button; Brett A Wagner; Garry R Buettner; Joseph J Cullen
Journal:  Free Radic Biol Med       Date:  2015-02-26       Impact factor: 7.376

4.  Mega-dose vitamin C as therapy for human cancer?

Authors:  Piet Borst
Journal:  Proc Natl Acad Sci U S A       Date:  2008-11-24       Impact factor: 11.205

5.  Formation of a vitamin C conjugate of acrolein and its paraoxonase-mediated conversion into 5,6,7,8-tetrahydroxy-4-oxooctanal.

Authors:  Nicholas G Kesinger; Brandi L Langsdorf; Alexandre F Yokochi; Cristobal L Miranda; Jan F Stevens
Journal:  Chem Res Toxicol       Date:  2010-04-19       Impact factor: 3.739

6.  Transcriptional profiling of genes involved in ascorbic acid biosynthesis, recycling, and degradation during three leaf developmental stages in celery.

Authors:  Wei Huang; Guang-Long Wang; Hui Li; Feng Wang; Zhi-Sheng Xu; Ai-Sheng Xiong
Journal:  Mol Genet Genomics       Date:  2016-09-07       Impact factor: 3.291

7.  Palmitoyl ascorbate-loaded polymeric micelles: cancer cell targeting and cytotoxicity.

Authors:  Rupa R Sawant; Onkar Vaze; Gerard G M D'Souza; Karen Rockwell; Vladimir P Torchilin
Journal:  Pharm Res       Date:  2010-08-21       Impact factor: 4.200

8.  Vitamin C improves the quality of somatic cell reprogramming.

Authors:  Miguel A Esteban; Duanqing Pei
Journal:  Nat Genet       Date:  2012-03-28       Impact factor: 38.330

9.  Influence of concurrent medications on outcomes of men with prostate cancer included in the TAX 327 study.

Authors:  Saroj Niraula; Greg Pond; Ronald de Wit; Mario Eisenberger; Ian F Tannock; Anthony M Joshua
Journal:  Can Urol Assoc J       Date:  2013 Jan-Feb       Impact factor: 1.862

10.  High dose concentration administration of ascorbic acid inhibits tumor growth in BALB/C mice implanted with sarcoma 180 cancer cells via the restriction of angiogenesis.

Authors:  Chang-Hwan Yeom; Gunsup Lee; Jin-Hee Park; Jaelim Yu; Seyeon Park; Sang-Yeop Yi; Hye Ree Lee; Young Seon Hong; Joosung Yang; Sukchan Lee
Journal:  J Transl Med       Date:  2009-08-11       Impact factor: 5.531

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