Literature DB >> 18681738

Label-free, all-electrical, in situ human epidermal growth receptor 2 detection.

Joseph A Capobianco1, Wan Y Shih, Qing-An Yuan, Gregory P Adams, Wei-Heng Shih.   

Abstract

Using 3-mercaptopropyltrimethoxysilane (MPS)-coated (PbMg 1/3 Nb 2/3 O3)0.63-(PbTiO3)0.37 (PMN-PT)/tin and lead zirconate titanate/glass piezoelectric microcantilever sensors (PEMSs) with single-chain variable fragment (scFv) immobilized on the MPS surface, we have demonstrated real-time, label-free detection of human epidermal growth factor receptor 2 (Her2) in a background of 1 mg/ml bovine serum albumin. Coupled with a scFv with a KD of 3.4 x 10(-8)M, the MPS-insulated PMN-PT/tin PEMS 560 microm long and 720 microm wide exhibited a Her2 concentration sensitivity of 5 ng/ml in a background of 1 mg/ml BSA.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18681738      PMCID： PMC2678786          DOI： 10.1063/1.2949831

Source DB:  PubMed          Journal:  Rev Sci Instrum        ISSN： 0034-6748            Impact factor:   1.523


  16 in total

Review 1.  Radioimmunotherapy with engineered antibodies.

Authors:  Maria G Russeva; Gregory P Adams
Journal:  Expert Opin Biol Ther       Date:  2004-02       Impact factor: 4.388

2.  Isolation of scFvs to in vitro produced extracellular domains of EGFR family members.

Authors:  Eva Horak; Tara Heitner; Matthew K Robinson; Heidi H Simmons; Jennifer Garrison; Maria Russeva; Polina Furmanova; Jianlong Lou; Yu Zhou; Qing-An Yuan; Louis M Weiner; Gregory P Adams; James D Marks
Journal:  Cancer Biother Radiopharm       Date:  2005-12       Impact factor: 3.099

3.  In situ, in-liquid, all-electrical detection of Salmonella typhimurium using lead titanate zirconate/gold-coated glass cantilevers at any dipping depth.

Authors:  Qing Zhu; Wan Y Shih; Wei-Heng Shih
Journal:  Biosens Bioelectron       Date:  2007-02-20       Impact factor: 10.618

4.  Clinical utility of serial serum c-erbB-2 determinations in the follow-up of breast cancer patients.

Authors:  Tanja Fehm; Gerhard Gebauer; Wolfram Jäger
Journal:  Breast Cancer Res Treat       Date:  2002-09       Impact factor: 4.872

5.  Isolation of anti-MISIIR scFv molecules from a phage display library by cell sorter biopanning.

Authors:  Qing-An Yuan; Matthew K Robinson; Heidi H Simmons; Maria Russeva; Gregory P Adams
Journal:  Cancer Immunol Immunother       Date:  2007-08-04       Impact factor: 6.968

6.  Real-Time, Label-Free, All-Electrical Detection of Salmonella typhimurium Using Lead Zirconate Titanate/Gold-Coated Glass Cantilevers at any Relative Humidity.

Authors:  Qing Zhu; Wan Y Shih; Wei-Heng Shih
Journal:  Sens Actuators B Chem       Date:  2007-08-08       Impact factor: 7.460

7.  Characterisation of an antibody coated microcantilever as a potential immuno-based biosensor.

Authors:  C Grogan; R Raiteri; G M O'Connor; T J Glynn; V Cunningham; M Kane; M Charlton; D Leech
Journal:  Biosens Bioelectron       Date:  2002-03       Impact factor: 10.618

8.  3-mercaptopropyltrimethoxysilane as insulating coating and surface for protein immobilization for piezoelectric microcantilever sensors.

Authors:  Joseph A Capobianco; Wan Y Shih; Wei-Heng Shih
Journal:  Rev Sci Instrum       Date:  2007-04       Impact factor: 1.523

9.  In situ detection of Bacillus anthracis spores using fully submersible, self-exciting, self-sensing PMN-PT/Sn piezoelectric microcantilevers.

Authors:  John-Paul McGovern; Wan Y Shih; Wei-Heng Shih
Journal:  Analyst       Date:  2007-06-18       Impact factor: 4.616

10.  Clinical utility of serum HER2/neu in monitoring and prediction of progression-free survival in metastatic breast cancer patients treated with trastuzumab-based therapies.

Authors:  Francisco J Esteva; Carol D Cheli; Herbert Fritsche; Monica Fornier; Dennis Slamon; Robert P Thiel; Diana Luftner; Farooq Ghani
Journal:  Breast Cancer Res       Date:  2005-04-08       Impact factor: 6.466
View more
  9 in total

1.  Highly sensitive detection of HER2 extracellular domain in the serum of breast cancer patients by piezoelectric microcantilevers.

Authors:  LiNa Loo; Joseph A Capobianco; Wei Wu; Xiaotong Gao; Wan Y Shih; Wei-Heng Shih; Kambiz Pourrezaei; Matthew K Robinson; Gregory P Adams
Journal:  Anal Chem       Date:  2011-03-30       Impact factor: 6.986

2.  Immunoelectrochemical detection of the human epidermal growth factor receptor 2 (HER2) via gold nanoparticle-based rolling circle amplification.

Authors:  Congcong Shen; Shuping Liu; Xiaoqing Li; Dan Zhao; Minghui Yang
Journal:  Mikrochim Acta       Date:  2018-11-13       Impact factor: 5.833

3.  Label free detection of white spot syndrome virus using lead magnesium niobate-lead titanate piezoelectric microcantilever sensors.

Authors:  Joseph A Capobianco; Wei-Heng Shih; Jiann-Horng Leu; Grace Chu-Fang Lo; Wan Y Shih
Journal:  Biosens Bioelectron       Date:  2010-08-11       Impact factor: 10.618

Review 4.  Recombinant antibodies and their use in biosensors.

Authors:  Xiangqun Zeng; Zhihong Shen; Ray Mernaugh
Journal:  Anal Bioanal Chem       Date:  2011-12-13       Impact factor: 4.142

5.  Array lead zirconate titanate/glass piezoelectric microcantilevers for real-time detection of Bacillus anthracis with 10 spores/ml sensitivity and 1/1000 selectivity in bacterial mixtures.

Authors:  John-Paul McGovern; Wei-Heng Shih; Richard F Rest; Mitali Purohit; Mark Mattiucci; Kambiz Pourrezaei; Banu Onaral; Wan Y Shih
Journal:  Rev Sci Instrum       Date:  2009-12       Impact factor: 1.523

6.  Label-free Growth Receptor-2 Detection and Dissociation Constant Assessment in Diluted Human Serum Using a Longitudinal Extension Mode of a Piezoelectric Microcantilever Sensor.

Authors:  Joseph A Capobianco; Wan Y Shih; Gregory P Adams; Wei-Heng Shih
Journal:  Sens Actuators B Chem       Date:  2011-12-15       Impact factor: 7.460

Review 7.  Label-free technologies for quantitative multiparameter biological analysis.

Authors:  Abraham J Qavi; Adam L Washburn; Ji-Yeon Byeon; Ryan C Bailey
Journal:  Anal Bioanal Chem       Date:  2009-02-17       Impact factor: 4.142

8.  A rapid method to regenerate piezoelectric microcantilever sensors (PEMS).

Authors:  LiNa Loo; Wei Wu; Wan Y Shih; Wei-Heng Shih; Hossein Borghaei; Kambiz Pourrezaei; Gregory P Adams
Journal:  Sensors (Basel)       Date:  2011       Impact factor: 3.576

9.  Sensitive sandwich-type voltammetric immunosensor for breast cancer biomarker HER2 detection based on gold nanoparticles decorated Cu-MOF and Cu2ZnSnS4 NPs/Pt/g-C3N4 composite.

Authors:  Mehmet Lütfi Yola
Journal:  Mikrochim Acta       Date:  2021-02-10       Impact factor: 5.833
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.