PURPOSE: Conflicting data exist about the difference between 8- and 16-frame gated single-photon emission computed tomography (SPECT) left ventricular volumes and ejection fraction (EF); moreover, the influence of framing on detection of stress-induced functional changes is unknown. METHODS: In 133 patients, two separate gated SPECT studies, one with 8 and one with 16 frames, were simultaneously acquired during a single gantry orbit using dedicated software. In 33 of 133 patients, two additional studies (with 8 and 16 frames, respectively) were acquired using arrhythmia rejection. Left ventricular EF and volumes were calculated using the QGS software. Stress-induced ischemia was identified on summed perfusion images. RESULTS: Arrhythmia-rejection did not influence volumes and EF independently of framing rate. Using data without arrhythmia-rejection, there was a significant difference in volumes and EF between 8 and 16 frames both in resting and post-stress gated SPECT. However, the difference was small: 2.6% for resting and 2.8% for post-stress EF. Both using 8 and 16 frames, there were significantly larger volumes and lower EF in patients with than without stress-induced ischemia. A stress-induced decrease >5 EF units was observed in 26 of 133 patients using 8 and in 23 of 133 using 16 frames, respectively, with finding agreement in 19 patients. CONCLUSIONS: Comparing two simultaneously acquired studies, the use of 16 instead of 8 frames has minor and predictable influence on functional data. Furthermore, there are no differences in the detection of stress-induced functional changes. The advantage of 16 over 8 frames in the daily clinical practice appears questionable.
PURPOSE: Conflicting data exist about the difference between 8- and 16-frame gated single-photon emission computed tomography (SPECT) left ventricular volumes and ejection fraction (EF); moreover, the influence of framing on detection of stress-induced functional changes is unknown. METHODS: In 133 patients, two separate gated SPECT studies, one with 8 and one with 16 frames, were simultaneously acquired during a single gantry orbit using dedicated software. In 33 of 133 patients, two additional studies (with 8 and 16 frames, respectively) were acquired using arrhythmia rejection. Left ventricular EF and volumes were calculated using the QGS software. Stress-induced ischemia was identified on summed perfusion images. RESULTS:Arrhythmia-rejection did not influence volumes and EF independently of framing rate. Using data without arrhythmia-rejection, there was a significant difference in volumes and EF between 8 and 16 frames both in resting and post-stress gated SPECT. However, the difference was small: 2.6% for resting and 2.8% for post-stress EF. Both using 8 and 16 frames, there were significantly larger volumes and lower EF in patients with than without stress-induced ischemia. A stress-induced decrease >5 EF units was observed in 26 of 133 patients using 8 and in 23 of 133 using 16 frames, respectively, with finding agreement in 19 patients. CONCLUSIONS: Comparing two simultaneously acquired studies, the use of 16 instead of 8 frames has minor and predictable influence on functional data. Furthermore, there are no differences in the detection of stress-induced functional changes. The advantage of 16 over 8 frames in the daily clinical practice appears questionable.
Authors: Jacco J N Visser; Ellinor Busemann Sokole; Hein J Verberne; Jan B A Habraken; Huybert J F van de Stadt; Joris E N Jaspers; Morgan Shehata; Paul M Heeman; Berthe L F van Eck-Smit Journal: Eur J Nucl Med Mol Imaging Date: 2004-02 Impact factor: 9.236
Authors: L L Johnson; S A Verdesca; W Y Aude; R C Xavier; L T Nott; M W Campanella; G Germano Journal: J Am Coll Cardiol Date: 1997-12 Impact factor: 24.094
Authors: J C Stollfuss; F Haas; I Matsunari; J Neverve; S Nekolla; J Schneider-Eicke; U Schricke; S Ziegler; M Schwaiger Journal: Eur J Nucl Med Date: 1998-05
Authors: Cigdem Akincioglu; Daniel S Berman; Hidetaka Nishina; Paul B Kavanagh; Piotr J Slomka; Aiden Abidov; Sean Hayes; John D Friedman; Guido Germano Journal: J Nucl Med Date: 2005-07 Impact factor: 10.057
Authors: T M Bateman; D S Berman; G V Heller; K A Brown; M D Cerqueira; M S Verani; J E Udelson Journal: J Nucl Cardiol Date: 1999 Jul-Aug Impact factor: 3.872
Authors: Maghsoud Sarebani; Mohammad Bagher Shiran; Ahmad Bitarafan-Rajabi; Feridoon Rastgou; Zahra Ojaghi Haghighi; Ali Abbasian Ardakani Journal: Med J Islam Repub Iran Date: 2020-06-03