| Literature DB >> 18646266 |
B Giraudeau1, P Ravaud, A Donner.
Abstract
The cluster randomized cross-over design has been proposed in particular because it prevents an imbalance that may bring into question the internal validity of parallel group cluster trials. We derived a sample size formula for continuous outcomes that takes into account both the intraclass correlation coefficient (representing the clustering effect) and the interperiod correlation (induced by the cross-over design). Copyright (c) 2008 John Wiley & Sons, Ltd.Mesh:
Substances:
Year: 2008 PMID: 18646266 DOI: 10.1002/sim.3383
Source DB: PubMed Journal: Stat Med ISSN: 0277-6715 Impact factor: 2.373