Literature DB >> 18636263

Penile preserving surgery and surgical strategies to maximize penile form and function in penile cancer: recommendations from the United Kingdom experience.

Paul K Hegarty1, Majid Shabbir, Ben Hughes, Suks Minhas, Matthew Perry, Nicholas Watkin, David J Ralph.   

Abstract

OBJECTIVES: The diagnosis of penile cancer can be devastating for a man and his partner. The fear of cancer is heightened by the prospect of penile amputation. While conventional radical surgery continues to be an effective approach to management, the emasculating nature of this treatment has serious psychological and sexual morbidity. Recent studies have challenged the traditional belief that a 2 cm margin was required for adequate oncological control.
METHODS: We review the current options and status of such penile preserving techniques in the modern day management of penile cancer, and assess the use of the different techniques according to the stage and grade of disease based upon the combined experience of two superregional centres in the United Kingdom.
RESULTS: A range of organ preserving procedures matches the clinical spectrum of patients presenting with penile cancer. These demonstrate excellent oncological control whilst maximizing penile function and form.
CONCLUSION: Innovative surgical techniques can now preserve as much penile tissue and functional integrity as possible, without compromising oncological control. This minimizes the impact of disease and its treatment on the quality of life of the patient.

Entities:  

Mesh:

Year:  2008        PMID: 18636263     DOI: 10.1007/s00345-008-0312-x

Source DB:  PubMed          Journal:  World J Urol        ISSN: 0724-4983            Impact factor:   4.226


  27 in total

1.  Organ-sparing surgery for invasive penile cancer: early follow-up data.

Authors:  Peter Pietrzak; Cathy Corbishley; Nicholas Watkin
Journal:  BJU Int       Date:  2004-12       Impact factor: 5.588

2.  Penis conserving treatment for T1 and T2 penile carcinoma: clinical implications of a local recurrence.

Authors:  A P Lont; M P W Gallee; W Meinhardt; H van Tinteren; S Horenblas
Journal:  J Urol       Date:  2006-08       Impact factor: 7.450

3.  Forearm flap in one-stage reconstruction of the penis.

Authors:  T S Chang; W Y Hwang
Journal:  Plast Reconstr Surg       Date:  1984-08       Impact factor: 4.730

4.  The histological extent of the local spread of carcinoma of the penis and its therapeutic implications.

Authors:  A Agrawal; D Pai; N Ananthakrishnan; S R Smile; C Ratnakar
Journal:  BJU Int       Date:  2000-02       Impact factor: 5.588

5.  Glansectomy: an alternative surgical treatment for Buschke-Löwenstein tumors of the penis.

Authors:  D G Hatzichristou; A Apostolidis; V Tzortzis; K Hatzimouratidis; E Ioannides; K Yannakoyorgos
Journal:  Urology       Date:  2001-05       Impact factor: 2.649

6.  What surgical resection margins are required to achieve oncological control in men with primary penile cancer?

Authors:  Suks Minhas; Oliver Kayes; Paul Hegarty; Pardeep Kumar; Alex Freeman; David Ralph
Journal:  BJU Int       Date:  2005-11       Impact factor: 5.588

7.  Squamous cell carcinoma of the penis. IV. Prognostic factors of survival: analysis of tumor, nodes and metastasis classification system.

Authors:  S Horenblas; H van Tinteren
Journal:  J Urol       Date:  1994-05       Impact factor: 7.450

8.  A 10-year retrospective audit of penile cancer management in the UK.

Authors:  Tina Mistry; Rob W A Jones; Erica Dannatt; Krishna K Prasad; Andrew D Stockdale
Journal:  BJU Int       Date:  2007-09-10       Impact factor: 5.588

9.  The results of primary radiation therapy in the management of squamous cell carcinoma of the penis.

Authors:  M McLean; A M Akl; P Warde; R Bissett; T Panzarella; M Gospodarowicz
Journal:  Int J Radiat Oncol Biol Phys       Date:  1993-03-15       Impact factor: 7.038

10.  Quality of life in patients treated for penile cancer. A follow-up study.

Authors:  S Opjordsmoen; S D Fosså
Journal:  Br J Urol       Date:  1994-11
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  13 in total

1.  Sexual function after surgical treatment for penile cancer: Which organ-sparing approach gives the best results?

Authors:  Omid Sedigh; Marco Falcone; Carlo Ceruti; Massimiliano Timpano; Mirko Preto; Marco Oderda; Franklin Kuehhas; Mattia Sibona; Arianna Gillo; Paolo Gontero; Luigi Rolle; Bruno Frea
Journal:  Can Urol Assoc J       Date:  2015 Jul-Aug       Impact factor: 1.862

2.  Surgical treatment of primary disease for penile squamous cell carcinoma: A Surveillance, Epidemiology, and End Results database analysis.

Authors:  Yao Zhu; Wei-Jie Gu; Hong-Kai Wang; Cheng-Yuan Gu; Ding-Wei Ye
Journal:  Oncol Lett       Date:  2015-05-18       Impact factor: 2.967

Review 3.  Penile preserving and reconstructive surgery in the management of penile cancer.

Authors:  Arthur L Burnett
Journal:  Nat Rev Urol       Date:  2016-03-22       Impact factor: 14.432

4.  [Penile carcinoma: diagnosis and therapy].

Authors:  C Protzel; O W Hakenberg
Journal:  Urologe A       Date:  2013-01       Impact factor: 0.639

5.  Auricular Cartilage Composite Graft for Glans Reconstruction After Squamous Cell Carcinoma of the Penis.

Authors:  Masakatsu Hihara; Takashi Yamauchi; Natsuko Kakudo; Michika Fukui; Toshihito Mitsui; Yuki Matsuoka; Atsuyuki Kuro; Kenji Kusumoto
Journal:  Eplasty       Date:  2022-06-30

Review 6.  Review of penile reconstructive techniques.

Authors:  Sverrir Kristinsson; Mark Johnson; David Ralph
Journal:  Int J Impot Res       Date:  2020-03-09       Impact factor: 2.896

Review 7.  Progress on Management of Penile Cancer in 2020.

Authors:  Mohamed E Ahmed; Mahmoud I Khalil; Mohamed H Kamel; R Jeffrey Karnes; Philippe E Spiess
Journal:  Curr Treat Options Oncol       Date:  2020-11-23

8.  Current and future strategies in the diagnosis and management of penile cancer.

Authors:  Samuel M Lawindy; Alejandro R Rodriguez; Simon Horenblas; Philippe E Spiess
Journal:  Adv Urol       Date:  2011-05-30

Review 9.  Sexual function in the penile cancer survivor: a narrative review.

Authors:  Florian A Stroie; Matthew D Houlihan; Tobias S Kohler
Journal:  Transl Androl Urol       Date:  2021-06

Review 10.  Modern management of penile cancer.

Authors:  V Khoo
Journal:  EJC Suppl       Date:  2013-09
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