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Literature DB >> 1862077

Error filtration, interference, and the human linkage map.

D C Shields¹, A Collins, K H Buetow, N E Morton.

Abstract

Typing error is a major problem in constructing human linkage maps, leading to incorrect orders and inflating map lengths. An error filter is incorporated into multiple pairwise analysis that corrects for inflation of map lengths and improves recovery of the correct order. Multipoint mapping is more sensitive to error, but when its output is adjusted for both error and interference, map lengths are no longer inflated in proportion to the number of loci and are close to those obtained by multiple pairwise analysis.

Entities: Species

Mesh：

Year: 1991 PMID： 1862077 PMCID： PMC52113 DOI： 10.1073/pnas.88.15.6501

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

15 in total

1. Sequential tests for the detection of linkage.

Authors: N E MORTON
Journal: Am J Hum Genet Date: 1955-09 Impact factor: 11.025

2. Standard maps of chromosome 10.

Authors: N E Morton; A Collins
Journal: Ann Hum Genet Date: 1990-07 Impact factor: 1.670

3. Guidelines for human linkage maps: an international system for human linkage maps (ISLM, 1990).

Authors: B J Keats; S L Sherman; N E Morton; E B Robson; K H Buetow; P E Cartwright; A Chakravarti; U Francke; P P Green; J Ott
Journal: Genomics Date: 1991-03 Impact factor: 5.736

4. The CEPH consortium linkage map of human chromosome 1.

Authors: N C Dracopoli; P O'Connell; T I Elsner; J M Lalouel; R L White; K H Buetow; D Y Nishimura; J C Murray; C Helms; S K Mishra
Journal: Genomics Date: 1991-04 Impact factor: 5.736

5. MAP, an expert system for multiple pairwise linkage analysis.

Authors: N E Morton; V Andrews
Journal: Ann Hum Genet Date: 1989-07 Impact factor: 1.670

6. A common language for physical mapping of the human genome.

Authors: M Olson; L Hood; C Cantor; D Botstein
Journal: Science Date: 1989-09-29 Impact factor: 47.728

7. Tests of hypotheses on recombination frequencies.

Authors: N E Morton; C J MacLean; R Lew
Journal: Genet Res Date: 1985-06 Impact factor: 1.588

8. A mapping function for man.

Authors: D C Rao; N E Morton; J Lindsten; M Hultén; S Yee
Journal: Hum Hered Date: 1977 Impact factor: 0.444

9. Guidelines for human linkage maps. An International System for Human Linkage Maps (ISLM, 1990).

Authors: B J Keats; S L Sherman; N E Morton; E B Robson; K H Buetow; P E Cartwright; A Chakravarti; U Francke; P P Green; J Ott
Journal: Ann Hum Genet Date: 1991-01 Impact factor: 1.670

10. Construction of multilocus genetic linkage maps in humans.

Authors: E S Lander; P Green
Journal: Proc Natl Acad Sci U S A Date: 1987-04 Impact factor: 11.205

26 in total

1. A novel X-linked dominant condition: X-linked congenital isolated ptosis.

Authors: T F McMullan; A R Collins; A G Tyers; D O Robinson
Journal: Am J Hum Genet Date: 2000-03-14 Impact factor: 11.025

2. Linkage analysis in the presence of errors I: complex-valued recombination fractions and complex phenotypes.

Authors: H H Göring; J D Terwilliger
Journal: Am J Hum Genet Date: 2000-03 Impact factor: 11.025

3. Characterization of human crossover interference.

Authors: K W Broman; J L Weber
Journal: Am J Hum Genet Date: 2000-05-08 Impact factor: 11.025

4. A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data.

Authors: D Gordon; S C Heath; X Liu; J Ott
Journal: Am J Hum Genet Date: 2001-07-05 Impact factor: 11.025

9. Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/disequilibrium test.

Authors: Adele A Mitchell; David J Cutler; Aravinda Chakravarti
Journal: Am J Hum Genet Date: 2003-02-13 Impact factor: 11.025

10. Linkage analysis in the presence of errors II: marker-locus genotyping errors modeled with hypercomplex recombination fractions.