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Literature DB >> 18617817

General anesthetics and molecular mechanisms of unconsciousness.

Stuart A Forman¹, Victor A Chin.

Abstract

Mesh：

Substances：
Anesthetics

Year: 2008 PMID： 18617817 PMCID： PMC3674880 DOI： 10.1097/AIA.0b013e3181755da5

Source DB: PubMed Journal: Int Anesthesiol Clin ISSN： 0020-5907

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59 in total

1. Differential effects of ketamine enantiomers on NMDA receptor currents in cultured neurons.

Authors: H U Zeilhofer; D Swandulla; G Geisslinger; K Brune
Journal: Eur J Pharmacol Date: 1992-03-17 Impact factor: 4.432

2. Effect of N-methyl-D-aspartate receptor epsilon1 subunit gene disruption of the action of general anesthetic drugs in mice.

Authors: Yuki Sato; Eiji Kobayashi; Takanori Murayama; Masayoshi Mishina; Norimasa Seo
Journal: Anesthesiology Date: 2005-03 Impact factor: 7.892

3. Bispectral analysis of the electroencephalogram does not predict responsiveness to verbal command in patients emerging from xenon anaesthesia.

Authors: T Goto; Y Nakata; H Saito; Y Ishiguro; Y Niimi; K Suwa; S Morita
Journal: Br J Anaesth Date: 2000-09 Impact factor: 9.166

4. Dexmedetomidine sedation during awake craniotomy for seizure resection: effects on electrocorticography.

Authors: Michael J Souter; Irene Rozet; Jeffrey G Ojemann; Karen J Souter; Mark D Holmes; Lorri Lee; Arthur M Lam
Journal: J Neurosurg Anesthesiol Date: 2007-01 Impact factor: 3.956

5. The interaction of isoflurane and protein kinase C-activators on sarcolemmal KATP channels.

Authors: Lawrence A Turner; Kazuhiro Fujimoto; Akihiro Suzuki; Anna Stadnicka; Zeljko J Bosnjak; Wai-Meng Kwok
Journal: Anesth Analg Date: 2005-06 Impact factor: 5.108

6. Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentration.

Authors: Karin M Gerstin; Diane H Gong; Mona Abdallah; Bruce D Winegar; Edmond I Eger; Andrew T Gray
Journal: Anesth Analg Date: 2003-05 Impact factor: 5.108

7. Nonhalogenated alkane anesthetics fail to potentiate agonist actions on two ligand-gated ion channels.

Authors: D E Raines; R J Claycomb; M Scheller; S A Forman
Journal: Anesthesiology Date: 2001-08 Impact factor: 7.892

8. R (+) etomidate and the photoactivable R (+) azietomidate have comparable anesthetic activity in wild-type mice and comparably decreased activity in mice with a N265M point mutation in the gamma-aminobutyric acid receptor beta3 subunit.

Authors: Mark Liao; James M Sonner; S Shaukat Husain; Keith W Miller; Rachel Jurd; Uwe Rudolph; Edmond I Eger
Journal: Anesth Analg Date: 2005-07 Impact factor: 5.108

9. Stereospecific interaction of ketamine with nicotinic acetylcholine receptors in human sympathetic ganglion-like SH-SY5Y cells.

Authors: P Friederich; A Dybek; B W Urban
Journal: Anesthesiology Date: 2000-09 Impact factor: 7.892

10. Reduced sensitivity to ketamine and pentobarbital in mice lacking the N-methyl-D-aspartate receptor GluRepsilon1 subunit.

Authors: Andrey B Petrenko; Tomohiro Yamakura; Naoshi Fujiwara; Ahmed R Askalany; Hiroshi Baba; Kenji Sakimura
Journal: Anesth Analg Date: 2004-10 Impact factor: 5.108

17 in total

General anesthetics and molecular mechanisms of unconsciousness.

1. Differential effects of ketamine enantiomers on NMDA receptor currents in cultured neurons.

2. Effect of N-methyl-D-aspartate receptor epsilon1 subunit gene disruption of the action of general anesthetic drugs in mice.

3. Bispectral analysis of the electroencephalogram does not predict responsiveness to verbal command in patients emerging from xenon anaesthesia.

4. Dexmedetomidine sedation during awake craniotomy for seizure resection: effects on electrocorticography.

5. The interaction of isoflurane and protein kinase C-activators on sarcolemmal KATP channels.

6. Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentration.

7. Nonhalogenated alkane anesthetics fail to potentiate agonist actions on two ligand-gated ion channels.

8. R (+) etomidate and the photoactivable R (+) azietomidate have comparable anesthetic activity in wild-type mice and comparably decreased activity in mice with a N265M point mutation in the gamma-aminobutyric acid receptor beta3 subunit.

9. Stereospecific interaction of ketamine with nicotinic acetylcholine receptors in human sympathetic ganglion-like SH-SY5Y cells.

10. Reduced sensitivity to ketamine and pentobarbital in mice lacking the N-methyl-D-aspartate receptor GluRepsilon1 subunit.

Review 1. GABA_A receptor: Positive and negative allosteric modulators.

2. Mechanistic insights into xenon inhibition of NMDA receptors from MD simulations.

3. Isoflurane disrupts excitatory neurotransmitter dynamics via inhibition of mitochondrial complex I.

4. Neurophysiological correlates of sevoflurane-induced unconsciousness.

5. Inhalational anaesthetics and n-alcohols share a site of action in the neuronal Shaw2 Kv channel.

Review 6. Anesthetic considerations in patients with mitochondrial defects.

7. Investigation of the Role of Stimulation and Blockade of 5-HT₇ Receptors in Ketamine Anesthesia.

8. Disruption of frontal-parietal communication by ketamine, propofol, and sevoflurane.

9. Altered anesthetic sensitivity of mice lacking Ndufs4, a subunit of mitochondrial complex I.

10. General Anesthetic Conditions Induce Network Synchrony and Disrupt Sensory Processing in the Cortex.

Review 1. GABAA receptor: Positive and negative allosteric modulators.

Review 6. Anesthetic considerations in patients with mitochondrial defects.

Review 1. GABA_A receptor: Positive and negative allosteric modulators.