Literature DB >> 18532870

3D reconstruction and manufacture of real abdominal aortic aneurysms: from CT scan to silicone model.

B J Doyle1, L G Morris, A Callanan, P Kelly, D A Vorp, T M McGloughlin.   

Abstract

Abdominal aortic aneurysm (AAA) can be defined as a permanent and irreversible dilation of the infrarenal aorta. AAAs are often considered to be an aorta with a diameter 1.5 times the normal infrarenal aorta diameter. This paper describes a technique to manufacture realistic silicone AAA models for use with experimental studies. This paper is concerned with the reconstruction and manufacturing process of patient-specific AAAs. 3D reconstruction from computed tomography scan data allows the AAA to be created. Mould sets are then designed for these AAA models utilizing computer aided designcomputer aided manufacture techniques and combined with the injection-moulding method. Silicone rubber forms the basis of the resulting AAA model. Assessment of wall thickness and overall percentage difference from the final silicone model to that of the computer-generated model was performed. In these realistic AAA models, wall thickness was found to vary by an average of 9.21%. The percentage difference in wall thickness recorded can be attributed to the contraction of the casting wax and the expansion of the silicone during model manufacture. This method may be used in conjunction with wall stress studies using the photoelastic method or in fluid dynamic studies using a laser-Doppler anemometry. In conclusion, these patient-specific rubber AAA models can be used in experimental investigations, but should be assessed for wall thickness variability once manufactured.

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Year:  2008        PMID: 18532870     DOI: 10.1115/1.2907765

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  12 in total

1.  Improved assessment and treatment of abdominal aortic aneurysms: the use of 3D reconstructions as a surgical guidance tool in endovascular repair.

Authors:  B J Doyle; P A Grace; E G Kavanagh; P E Burke; F Wallis; M T Walsh; T M McGloughlin
Journal:  Ir J Med Sci       Date:  2009-03-25       Impact factor: 1.568

2.  An experimental and numerical comparison of the rupture locations of an abdominal aortic aneurysm.

Authors:  Barry J Doyle; Timothy J Corbett; Anthony Callanan; Michael T Walsh; David A Vorp; Timothy M McGloughlin
Journal:  J Endovasc Ther       Date:  2009-06       Impact factor: 3.487

3.  3D-Printed Tissue-Mimicking Phantoms for Medical Imaging and Computational Validation Applications.

Authors:  Aidan J Cloonan; Danial Shahmirzadi; Ronny X Li; Barry J Doyle; Elisa E Konofagou; Tim M McGloughlin
Journal:  3D Print Addit Manuf       Date:  2014-03-01       Impact factor: 5.449

4.  Engineering silicone rubbers for in vitro studies: creating AAA models and ILT analogues with physiological properties.

Authors:  T J Corbett; B J Doyle; A Callanan; M T Walsh; T M McGloughlin
Journal:  J Biomech Eng       Date:  2010-01       Impact factor: 2.097

5.  Identification of rupture locations in patient-specific abdominal aortic aneurysms using experimental and computational techniques.

Authors:  Barry J Doyle; Aidan J Cloonan; Michael T Walsh; David A Vorp; Timothy M McGloughlin
Journal:  J Biomech       Date:  2010-02-12       Impact factor: 2.712

6.  Experimental modelling of aortic aneurysms: novel applications of silicone rubbers.

Authors:  Barry J Doyle; Timothy J Corbett; Aidan J Cloonan; Michael R O'Donnell; Michael T Walsh; David A Vorp; Timothy M McGloughlin
Journal:  Med Eng Phys       Date:  2009-10       Impact factor: 2.242

7.  A novel measurement technique for the design of fenestrated stent grafts: Comparison with three-dimensional aorta models.

Authors:  Ji Hoon You; Sung-Gwon Kang; Bong Man Kim
Journal:  Exp Clin Cardiol       Date:  2013

8.  Vessel asymmetry as an additional diagnostic tool in the assessment of abdominal aortic aneurysms.

Authors:  Barry J Doyle; Anthony Callanan; Paul E Burke; Pierce A Grace; Michael T Walsh; David A Vorp; Timothy M McGloughlin
Journal:  J Vasc Surg       Date:  2008-11-22       Impact factor: 4.268

9.  Effect of manufacturing and experimental conditions on the mechanical and surface properties of silicone elastomer scaffolds used in endothelial mechanobiological studies.

Authors:  Marc-Antoine Campeau; Audrey Lortie; Pierrick Tremblay; Marc-Olivier Béliveau; Dominic Dubé; Ève Langelier; Léonie Rouleau
Journal:  Biomed Eng Online       Date:  2017-07-14       Impact factor: 2.819

10.  A comparison of modelling techniques for computing wall stress in abdominal aortic aneurysms.

Authors:  Barry J Doyle; Anthony Callanan; Timothy M McGloughlin
Journal:  Biomed Eng Online       Date:  2007-10-19       Impact factor: 2.819

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