Literature DB >> 18472889

Efficacy and Tolerance of Single-dose Azithromycin for Treatment of Chlamydial Cervicitis During Pregnancy.

J M Miller1.   

Abstract

OBJECTIVE: The intent of this study was to determine the efficacy and tolerance of single-dose oral azithromycin in the treatment of pregnant women with endocervical chlamydial carriage.
METHODS: A retrospective review of clinic records over a two-year period identified pregnant patients treated with a single 1-g dose of azithromycin for chlamydial carriage. The side effects and subsequent chlamydial carriage (test of cure) were noted.
RESULTS: A total of 146 pregnant women treated with azithromycin was reviewed. A cure rate of 96% was found. Side effects were reported in 5%.
CONCLUSIONS: A single 1-g oral dose of azithromycin is effective for the treatment of chlamydia and is well tolerated in pregnant women.

Entities:  

Year:  1995        PMID: 18472889      PMCID: PMC2366150          DOI: 10.1155/S1064744995000597

Source DB:  PubMed          Journal:  Infect Dis Obstet Gynecol        ISSN: 1064-7449


  10 in total

1.  Treatment of Chlamydia trachomatis infections: comparison of 1- and 2-g doses of erythromycin daily for seven days.

Authors:  C C Linnemann; C L Heaton; M Ritchey
Journal:  Sex Transm Dis       Date:  1987 Apr-Jun       Impact factor: 2.830

2.  Double-blind randomized study comparing amoxicillin and erythromycin for the treatment of Chlamydia trachomatis in pregnancy.

Authors:  A H Magat; L S Alger; D A Nagey; V Hatch; J C Lovchik
Journal:  Obstet Gynecol       Date:  1993-05       Impact factor: 7.661

3.  A controlled trial of a single dose of azithromycin for the treatment of chlamydial urethritis and cervicitis. The Azithromycin for Chlamydial Infections Study Group.

Authors:  D H Martin; T F Mroczkowski; Z A Dalu; J McCarty; R B Jones; S J Hopkins; R B Johnson
Journal:  N Engl J Med       Date:  1992-09-24       Impact factor: 91.245

4.  Comparison of the Clearview Chlamydia, the PACE 2 assay, and culture for detection of Chlamydia trachomatis from cervical specimens in a low-prevalence population.

Authors:  J Blanding; L Hirsch; N Stranton; T Wright; S Aarnaes; L de la Maza; E M Peterson
Journal:  J Clin Microbiol       Date:  1993-06       Impact factor: 5.948

5.  Comparative evaluation of detection assays for Chlamydia trachomatis.

Authors:  R Warren; B Dwyer; M Plackett; K Pettit; N Rizvi; A M Baker
Journal:  J Clin Microbiol       Date:  1993-06       Impact factor: 5.948

6.  Amoxicillin therapy for Chlamydia trachomatis in pregnancy.

Authors:  W R Crombleholme; J Schachter; M Grossman; D V Landers; R L Sweet
Journal:  Obstet Gynecol       Date:  1990-05       Impact factor: 7.661

7.  Risk factors for recurrent Chlamydia trachomatis infections in women.

Authors:  S D Hillis; A Nakashima; P A Marchbanks; D G Addiss; J P Davis
Journal:  Am J Obstet Gynecol       Date:  1994-03       Impact factor: 8.661

8.  A randomized, prospective trial comparing amoxicillin and erythromycin for the treatment of Chlamydia trachomatis in pregnancy.

Authors:  N S Silverman; M Sullivan; M Hochman; M Womack; D L Jungkind
Journal:  Am J Obstet Gynecol       Date:  1994-03       Impact factor: 8.661

9.  Compliance with antibiotic therapy for Chlamydia trachomatis and Neisseria gonorrhoeae.

Authors:  B P Katz; B W Zwickl; V A Caine; R B Jones
Journal:  Sex Transm Dis       Date:  1992 Nov-Dec       Impact factor: 2.830

10.  Azithromycin and erythromycin in the treatment of cervical chlamydial infection during pregnancy.

Authors:  M R Bush; C Rosa
Journal:  Obstet Gynecol       Date:  1994-07       Impact factor: 7.661

  10 in total
  4 in total

Review 1.  Concurrent gonococcal and chlamydial infection: how best to treat.

Authors:  A J Robinson; G L Ridgway
Journal:  Drugs       Date:  2000-04       Impact factor: 9.546

2.  Treatment of Chlamydia trachomatis infections in pregnant women.

Authors:  J M Miller; D H Martin
Journal:  Drugs       Date:  2000-09       Impact factor: 9.546

3.  Open study of the safety and efficacy of a single oral dose of cefixime for the treatment of gonorrhea in pregnancy.

Authors:  J M Miller
Journal:  Infect Dis Obstet Gynecol       Date:  1997

Review 4.  On the pathway to better birth outcomes? A systematic review of azithromycin and curable sexually transmitted infections.

Authors:  R Matthew Chico; Berkin B Hack; Melanie J Newport; Enesia Ngulube; Daniel Chandramohan
Journal:  Expert Rev Anti Infect Ther       Date:  2013-11-06       Impact factor: 5.091

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.