OBJECTIVE: We evaluated risk factors for recurrent Chlamydia trachomatis infections in women. STUDY DESIGN: We used a retrospective cohort design to examine predictors of recurrent infection in the 38,866 female residents of Wisconsin whose first reported C. trachomatis infection occurred between 1985 and 1989. RESULTS: Young age at first reported infection was the strongest predictor of recurrent C. trachomatis infection, after adjustment for covariates. Adolescents < 15 years old had an eightfold increased risk, those 15 to 19 years old had a fivefold increased risk, and women 20 to 29 years old had a twofold increased risk of recurrent C. trachomatis infection, compared with that among women 30 to 44 years old. In 54% of those aged < 15 at initial infection and 30% of those aged 15 to 19, recurrence developed. Other characteristics associated with recurrence included black race, residence in Milwaukee County, coinfection with gonorrhea, and past sexually transmitted diseases; receiving care in a family-planning clinic appeared protective. CONCLUSIONS: Implementation of strategies to reduce the markedly elevated risk of recurrent chlamydia infections is urgently needed in female adolescents.
OBJECTIVE: We evaluated risk factors for recurrent Chlamydia trachomatis infections in women. STUDY DESIGN: We used a retrospective cohort design to examine predictors of recurrent infection in the 38,866 female residents of Wisconsin whose first reported C. trachomatis infection occurred between 1985 and 1989. RESULTS: Young age at first reported infection was the strongest predictor of recurrent C. trachomatis infection, after adjustment for covariates. Adolescents < 15 years old had an eightfold increased risk, those 15 to 19 years old had a fivefold increased risk, and women 20 to 29 years old had a twofold increased risk of recurrent C. trachomatis infection, compared with that among women 30 to 44 years old. In 54% of those aged < 15 at initial infection and 30% of those aged 15 to 19, recurrence developed. Other characteristics associated with recurrence included black race, residence in Milwaukee County, coinfection with gonorrhea, and past sexually transmitted diseases; receiving care in a family-planning clinic appeared protective. CONCLUSIONS: Implementation of strategies to reduce the markedly elevated risk of recurrent chlamydia infections is urgently needed in female adolescents.
Authors: D Scott Lamontagne; Kathleen Baster; Lynsey Emmett; Tom Nichols; Sarah Randall; Louise McLean; Paula Meredith; Veerakathy Harindra; Jean M Tobin; Gillian S Underhill; W Graham Hewitt; Jennifer Hopwood; Toni Gleave; Ajit K Ghosh; Harry Mallinson; Alisha R Davies; Gwenda Hughes; Kevin A Fenton Journal: Sex Transm Infect Date: 2006-10-18 Impact factor: 3.519
Authors: L M Niccolai; J R Ickovics; K Zeller; T S Kershaw; S Milan; J B Lewis; K A Ethier Journal: Sex Transm Infect Date: 2005-06 Impact factor: 3.519
Authors: Sandra J van Vliet; Liana Steeghs; Sven C M Bruijns; Medi M Vaezirad; Christian Snijders Blok; Jésus A Arenas Busto; Marcel Deken; Jos P M van Putten; Yvette van Kooyk Journal: PLoS Pathog Date: 2009-10-16 Impact factor: 6.823