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Literature DB >> 18452288

Synthesis of multimeric MR contrast agents for cellular imaging.

Ying Song¹, Ellen K Kohlmeir, Thomas J Meade.

Abstract

We have prepared a series of molecular multimeric MR contrast agents for cell labeling that are easy to synthesize, relatively low molecular weight, and biocompatible. The relaxivities of the agents range from 17 to 85 mM(-1) s(-1). Cellular uptake is concentration dependent and viability is excellent. MR images of cell pellets reveal a marked increase in observed signal intensity.

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Year: 2008 PMID： 18452288 PMCID： PMC2755520 DOI： 10.1021/ja0777990

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

19 in total

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Journal: Magn Reson Med Date: 2004-05 Impact factor: 4.668

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Authors: Gaëlle M Nicolle; Eva Tóth; Heribert Schmitt-Willich; Bernd Radüchel; André E Merbach
Journal: Chemistry Date: 2002-03-01 Impact factor: 5.236

9. Frequency and severity of acute allergic-like reactions to gadolinium-containing i.v. contrast media in children and adults.

Authors: Jonathan R Dillman; James H Ellis; Richard H Cohan; Peter J Strouse; Sophia C Jan
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Review 10. Multimodal MRI contrast agents.

Authors: Luca Frullano; Thomas J Meade
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42 in total

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Authors: Jessica Wahsner; Eric M Gale; Aurora Rodríguez-Rodríguez; Peter Caravan
Journal: Chem Rev Date: 2018-10-16 Impact factor: 60.622

8. Gadolinium-conjugated dendrimer nanoclusters as a tumor-targeted T1 magnetic resonance imaging contrast agent.

Authors: Zhiliang Cheng; Daniel L J Thorek; Andrew Tsourkas
Journal: Angew Chem Int Ed Engl Date: 2010 Impact factor: 15.336

9. DNA-gadolinium-gold nanoparticles for in vivo T1 MR imaging of transplanted human neural stem cells.

Authors: Francesca J Nicholls; Matthew W Rotz; Harmanvir Ghuman; Keith W MacRenaris; Thomas J Meade; Michel Modo
Journal: Biomaterials Date: 2015-11-14 Impact factor: 12.479

10. Demonstration of a sucrose-derived contrast agent for magnetic resonance imaging of the GI tract.

Authors: Gary V Martinez; Suryakiran Navath; Kamini Sewda; Venkataramanarao Rao; Parastou Foroutan; Ramesh Alleti; Valerie E Moberg; Ali M Ahad; Domenico Coppola; Mark C Lloyd; Robert J Gillies; David L Morse; Eugene A Mash
Journal: Bioorg Med Chem Lett Date: 2013-02-13 Impact factor: 2.823