Literature DB >> 18419266

The multiple facets of Per2.

U Albrecht1, A Bordon, I Schmutz, J Ripperger.   

Abstract

The Period 2 (Per2) gene is an important component of the circadian system. It appears to be not only part of the core oscillator mechanism, but also part of the input and output pathways of the clock. Because of its involvement at multiple levels of the circadian system, Per2 needs to meet a variety of different demands. We discuss how Per2 might be able to fulfill multiple functions by reviewing known facts and combine this with speculations based on these facts. This might provide new views about Per2 function and help to better understand diseases that are rooted in the circadian system.

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Year:  2007        PMID: 18419266     DOI: 10.1101/sqb.2007.72.001

Source DB:  PubMed          Journal:  Cold Spring Harb Symp Quant Biol        ISSN: 0091-7451


  33 in total

1.  Thermal stability analyses of human PERIOD-2 C-terminal domain using dynamic light scattering and circular dichroism.

Authors:  Yuejiao Xian; Brenda Moreno; Victoria Miranda; Neha Vijay; Luis C Nunez; Jennie Choi; Christian S Quinones; Paulina Rios; Neha Chauhan; Karla V Moriel; Noah J Ruelas; Adan E Castaneda; Ruben Cano Rodriguez; Bianca N Amezaga; Seham Z Azzam; Chuan Xiao
Journal:  PLoS One       Date:  2020-04-22       Impact factor: 3.240

Review 2.  Methods in field chronobiology.

Authors:  Davide M Dominoni; Susanne Åkesson; Raymond Klaassen; Kamiel Spoelstra; Martin Bulla
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2017-11-19       Impact factor: 6.237

Review 3.  Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action.

Authors:  Siddharth Sukumaran; Richard R Almon; Debra C DuBois; William J Jusko
Journal:  Adv Drug Deliv Rev       Date:  2010-06-11       Impact factor: 15.470

Review 4.  Genetic insights on sleep schedules: this time, it's PERsonal.

Authors:  S Y Christin Chong; Louis J Ptáček; Ying-Hui Fu
Journal:  Trends Genet       Date:  2012-08-28       Impact factor: 11.639

5.  Model-driven experimental approach reveals the complex regulatory distribution of p53 by the circadian factor Period 2.

Authors:  Tetsuya Gotoh; Jae Kyoung Kim; Jingjing Liu; Marian Vila-Caballer; Philip E Stauffer; John J Tyson; Carla V Finkielstein
Journal:  Proc Natl Acad Sci U S A       Date:  2016-11-09       Impact factor: 11.205

6.  The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors.

Authors:  Isabelle Schmutz; Jürgen A Ripperger; Stéphanie Baeriswyl-Aebischer; Urs Albrecht
Journal:  Genes Dev       Date:  2010-02-15       Impact factor: 11.361

7.  Casein kinase 1-dependent phosphorylation of familial advanced sleep phase syndrome-associated residues controls PERIOD 2 stability.

Authors:  Naval P Shanware; John A Hutchinson; Sang Hwa Kim; Lihong Zhan; Michael J Bowler; Randal S Tibbetts
Journal:  J Biol Chem       Date:  2011-02-15       Impact factor: 5.157

8.  Role of the circadian clock gene Per2 in adaptation to cold temperature.

Authors:  Sylvie Chappuis; Jürgen Alexander Ripperger; Anna Schnell; Gianpaolo Rando; Corinne Jud; Walter Wahli; Urs Albrecht
Journal:  Mol Metab       Date:  2013-05-10       Impact factor: 7.422

Review 9.  Circadian rhythms and metabolic syndrome: from experimental genetics to human disease.

Authors:  Eleonore Maury; Kathryn Moynihan Ramsey; Joseph Bass
Journal:  Circ Res       Date:  2010-02-19       Impact factor: 17.367

10.  Natural selection against a circadian clock gene mutation in mice.

Authors:  Kamiel Spoelstra; Martin Wikelski; Serge Daan; Andrew S I Loudon; Michaela Hau
Journal:  Proc Natl Acad Sci U S A       Date:  2015-12-29       Impact factor: 11.205

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