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Literature DB >> 18375377

Pluripotency and nuclear reprogramming.

Abstract

Embryonic stem cells are promising donor cell sources for cell transplantation therapy, which may in the future be used to treat various diseases and injuries. However, as is the case for organ transplantation, immune rejection after transplantation is a potential problem with this type of therapy. Moreover, the use of human embryos presents serious ethical difficulties. These issues may be overcome if pluripotent stem cells are generated from patients' somatic cells. Here, we review the molecular mechanisms underlying pluripotency and the currently known methods of inducing pluripotency in somatic cells.

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Transcription Factors

Year: 2008 PMID： 18375377 PMCID： PMC2610180 DOI： 10.1098/rstb.2008.2261

Source DB: PubMed Journal: Philos Trans R Soc Lond B Biol Sci ISSN： 0962-8436 Impact factor: 6.237

127 in total

1. Isolation and characterization of the murine Nanog gene promoter.

Authors: Da Yong Wu; Zhen Yao
Journal: Cell Res Date: 2005-05 Impact factor: 25.617

2. Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells.

Authors: M Tada; T Tada; L Lefebvre; S C Barton; M A Surani
Journal: EMBO J Date: 1997-11-03 Impact factor: 11.598

3. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides.

Authors: A G Smith; J K Heath; D D Donaldson; G G Wong; J Moreau; M Stahl; D Rogers
Journal: Nature Date: 1988-12-15 Impact factor: 49.962

4. Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling.

Authors: Menno F Kielman; Maaret Rindapää; Claudia Gaspar; Nicole van Poppel; Cor Breukel; Sandra van Leeuwen; Makoto Mark Taketo; Scott Roberts; Ron Smits; Riccardo Fodde
Journal: Nat Genet Date: 2002-11-11 Impact factor: 38.330

5. Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia.

Authors: K Wade Foster; Zhaoli Liu; Clinton D Nail; Xingnan Li; Thomas J Fitzgerald; Sarah K Bailey; Andra R Frost; Iuri D Louro; Tim M Townes; Andrew J Paterson; Jeffrey E Kudlow; Susan M Lobo-Ruppert; J Michael Ruppert
Journal: Oncogene Date: 2005-02-24 Impact factor: 9.867

6. A cat cloned by nuclear transplantation.

Authors: T Shin; D Kraemer; J Pryor; L Liu; J Rugila; L Howe; S Buck; K Murphy; L Lyons; M Westhusin
Journal: Nature Date: 2002-02-14 Impact factor: 49.962

7. Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression.

Authors: Takao Kuroda; Masako Tada; Hiroshi Kubota; Hironobu Kimura; Shin-ya Hatano; Hirofumi Suemori; Norio Nakatsuji; Takashi Tada
Journal: Mol Cell Biol Date: 2005-03 Impact factor: 4.272

8. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state.

Authors: Marius Wernig; Alexander Meissner; Ruth Foreman; Tobias Brambrink; Manching Ku; Konrad Hochedlinger; Bradley E Bernstein; Rudolf Jaenisch
Journal: Nature Date: 2007-06-06 Impact factor: 49.962

9. A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells.

Authors: Zirong Li; Sara Van Calcar; Chunxu Qu; Webster K Cavenee; Michael Q Zhang; Bing Ren
Journal: Proc Natl Acad Sci U S A Date: 2003-06-13 Impact factor: 11.205

10. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.

Authors: Masato Nakagawa; Michiyo Koyanagi; Koji Tanabe; Kazutoshi Takahashi; Tomoko Ichisaka; Takashi Aoi; Keisuke Okita; Yuji Mochiduki; Nanako Takizawa; Shinya Yamanaka
Journal: Nat Biotechnol Date: 2007-11-30 Impact factor: 54.908

53 in total

Review 1. The potential of adipose stem cells in regenerative medicine.

Authors: Bettina Lindroos; Riitta Suuronen; Susanna Miettinen
Journal: Stem Cell Rev Rep Date: 2011-06 Impact factor: 5.739

2. Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation.

Authors: Nathan Salomonis; Christopher R Schlieve; Laura Pereira; Christine Wahlquist; Alexandre Colas; Alexander C Zambon; Karen Vranizan; Matthew J Spindler; Alexander R Pico; Melissa S Cline; Tyson A Clark; Alan Williams; John E Blume; Eva Samal; Mark Mercola; Bradley J Merrill; Bruce R Conklin
Journal: Proc Natl Acad Sci U S A Date: 2010-05-24 Impact factor: 11.205

3. Bone transplantation and tissue engineering, part IV. Mesenchymal stem cells: history in orthopedic surgery from Cohnheim and Goujon to the Nobel Prize of Yamanaka.

Authors: Philippe Hernigou
Journal: Int Orthop Date: 2015-03-07 Impact factor: 3.075

Pluripotency and nuclear reprogramming.

1. Isolation and characterization of the murine Nanog gene promoter.

2. Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells.

3. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides.

4. Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling.

5. Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia.

6. A cat cloned by nuclear transplantation.

7. Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression.

8. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state.

9. A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells.

10. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.

Review 1. The potential of adipose stem cells in regenerative medicine.

2. Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation.

3. Bone transplantation and tissue engineering, part IV. Mesenchymal stem cells: history in orthopedic surgery from Cohnheim and Goujon to the Nobel Prize of Yamanaka.

Review 4. Advances in reprogramming somatic cells to induced pluripotent stem cells.

5. Introduction. Japan: its tradition and hot topics in biological sciences.

Review 6. The ageing immune system: is it ever too old to become young again?

7. Proteomics analysis of epithelial cells reprogrammed in cell-free extract.

Review 8. The potential for immunogenicity of autologous induced pluripotent stem cell-derived therapies.

9. Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells.

10. Stem cell platforms for regenerative medicine.