Literature DB >> 18338425

Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical "starter-unit effect".

Jason M Crawford1, Anna L Vagstad, Karen P Whitworth, Kenneth C Ehrlich, Craig A Townsend.   

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Year:  2008        PMID： 18338425      PMCID： PMC3182100          DOI： 10.1002/cbic.200700702

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  25 in total

Review 1.  Biosynthesis of polyketides (other than actinomycete macrolides).

Authors:  B J Rawlings
Journal:  Nat Prod Rep       Date:  1999-08       Impact factor: 13.423

2.  Secondary metabolite biosynthesis: the first century.

Authors:  R Bentley
Journal:  Crit Rev Biotechnol       Date:  1999       Impact factor: 8.429

Review 3.  Polyketide biosynthesis: a millennium review.

Authors:  J Staunton; K J Weissman
Journal:  Nat Prod Rep       Date:  2001-08       Impact factor: 13.423

Review 4.  Fatty acid synthase, a proficient multifunctional enzyme.

Authors:  S J Wakil
Journal:  Biochemistry       Date:  1989-05-30       Impact factor: 3.162

5.  The polyketide synthase gene pks4 from Gibberella fujikuroi encodes a key enzyme in the biosynthesis of the red pigment bikaverin.

Authors:  Pia Linnemannstöns; Jessica Schulte; Maria del Mar Prado; Robert H Proctor; Javier Avalos; Bettina Tudzynski
Journal:  Fungal Genet Biol       Date:  2002-11       Impact factor: 3.495

6.  Heterologous expression and product identification of Colletotrichum lagenarium polyketide synthase encoded by the PKS1 gene involved in melanin biosynthesis.

Authors:  I Fujii; Y Mori; A Watanabe; Y Kubo; G Tsuji; Y Ebizuka
Journal:  Biosci Biotechnol Biochem       Date:  1999-08       Impact factor: 2.043

7.  Aspergillus has distinct fatty acid synthases for primary and secondary metabolism.

Authors:  D W Brown; T H Adams; N P Keller
Journal:  Proc Natl Acad Sci U S A       Date:  1996-12-10       Impact factor: 11.205

8.  Unprecedented mechanism of chain length determination in fungal aromatic polyketide synthases.

Authors:  Akira Watanabe; Yutaka Ebizuka
Journal:  Chem Biol       Date:  2004-08

9.  Hydrolytic polyketide shortening by ayg1p, a novel enzyme involved in fungal melanin biosynthesis.

Authors:  Isao Fujii; Yoshinori Yasuoka; Huei-Fung Tsai; Yun C Chang; K J Kwon-Chung; Yutaka Ebizuka
Journal:  J Biol Chem       Date:  2004-08-13       Impact factor: 5.157

10.  Mechanism of the beta-ketoacyl synthase reaction catalyzed by the animal fatty acid synthase.

Authors:  Andrzej Witkowski; Anil K Joshi; Stuart Smith
Journal:  Biochemistry       Date:  2002-09-03       Impact factor: 3.162
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  18 in total

Review 1.  New insights into the formation of fungal aromatic polyketides.

Authors:  Jason M Crawford; Craig A Townsend
Journal:  Nat Rev Microbiol       Date:  2010-12       Impact factor: 60.633

2.  Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis.

Authors:  Jaclyn M Winter; Duilio Cascio; David Dietrich; Michio Sato; Kenji Watanabe; Michael R Sawaya; John C Vederas; Yi Tang
Journal:  J Am Chem Soc       Date:  2015-07-30       Impact factor: 15.419

3.  Demonstration of starter unit interprotein transfer from a fatty acid synthase to a multidomain, nonreducing polyketide synthase.

Authors:  Jennifer Foulke-Abel; Craig A Townsend
Journal:  Chembiochem       Date:  2012-07-13       Impact factor: 3.164

Review 4.  Unraveling polyketide synthesis in members of the genus Aspergillus.

Authors:  Yi-Ming Chiang; Berl R Oakley; Nancy P Keller; Clay C C Wang
Journal:  Appl Microbiol Biotechnol       Date:  2010-04-02       Impact factor: 4.813

Review 5.  Recent advancements in the biosynthetic mechanisms for polyketide-derived mycotoxins.

Authors:  Justin Huffman; Ryan Gerber; Liangcheng Du
Journal:  Biopolymers       Date:  2010-09       Impact factor: 2.505

6.  Navigating the fungal polyketide chemical space: from genes to molecules.

Authors:  Yit-Heng Chooi; Yi Tang
Journal:  J Org Chem       Date:  2012-09-13       Impact factor: 4.354

7.  Interrogation of global active site occupancy of a fungal iterative polyketide synthase reveals strategies for maintaining biosynthetic fidelity.

Authors:  Anna L Vagstad; Stefanie B Bumpus; Katherine Belecki; Neil L Kelleher; Craig A Townsend
Journal:  J Am Chem Soc       Date:  2012-04-09       Impact factor: 15.419

8.  Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus.

Authors:  Yuquan Xu; Patricia Espinosa-Artiles; Vivien Schubert; Ya-ming Xu; Wei Zhang; Min Lin; A A Leslie Gunatilaka; Roderich Süssmuth; István Molnár
Journal:  Appl Environ Microbiol       Date:  2013-01-18       Impact factor: 4.792

9.  Combinatorial domain swaps provide insights into the rules of fungal polyketide synthase programming and the rational synthesis of non-native aromatic products.

Authors:  Anna L Vagstad; Adam G Newman; Philip A Storm; Katherine Belecki; Jason M Crawford; Craig A Townsend
Journal:  Angew Chem Int Ed Engl       Date:  2013-01-02       Impact factor: 15.336

10.  Starter unit specificity directs genome mining of polyketide synthase pathways in fungi.

Authors:  Jason M Crawford; Anna L Vagstad; Kenneth C Ehrlich; Craig A Townsend
Journal:  Bioorg Chem       Date:  2008-01-22       Impact factor: 5.275
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