Literature DB >> 18327134

Macular hole surgery with triamcinolone acetonide-assisted internal limiting membrane peeling: one-year results.

Hiroyuki Nomoto1, Fumio Shiraga, Hidetaka Yamaji, Koki Fukuda, Tetsuya Baba, Ippei Takasu, Hiroshi Ohtsuki.   

Abstract

PURPOSE: To report the 1-year results of macular hole surgery with triamcinolone acetonide (TA)-assisted internal limiting membrane (ILM) peeling and to compare those with results of indocyanine green (ICG)-assisted ILM peeling.
METHODS: In a nonrandomized, retrospective, interventional case series, 40 eyes of 39 consecutive patients with idiopathic full-thickness macular holes underwent macular hole surgery with TA-assisted ILM peeling. Surgical results 1 year after surgery, including changes in best-corrected visual acuity (BCVA) and macular hole closure, were evaluated. Moreover, we compared the results for these 40 eyes (TA group) with those for 27 eyes of 27 consecutive patients who had undergone macular hole surgery with 0.25% ICG-assisted ILM peeling (ICG group).
RESULTS: In the TA group, macular holes were closed in 39 (98%) of 40 eyes. Mean BCVA +/- SD significantly improved from 0.78 +/- 0.31 logarithm of the minimal angle of resolution (logMAR) preoperatively to 0.20 +/- 0.30 logMAR (P < 0.001). BCVA improved by > or =0.2 logMAR in 37 eyes (93%). BCVA was 20/40 or better in 33 (83%) of 30 eyes. In the ICG group, macular holes were closed in all 27 eyes (100%), and mean BCVA +/- SD significantly improved from 0.81 +/- 0.4 logMAR preoperatively to 0.34 +/- 0.2 logMAR 1 year postoperatively (P < 0.001). BCVA improved by > or =0.2 logMAR in 22 eyes (81%). BCVA was 20/40 or better in 16 (59%) of 27 eyes. Significant differences between groups were seen in mean BCVA 1 year after surgery (P = 0.049) but not in BCVA of 20/40 or better (P = 0.17) or change in BCVA by > or =0.2 logMAR (P = 0.05).
CONCLUSION: TA is useful as an adjuvant for ILM peeling in macular hole surgery, and BCVA 1 year after surgery might be more favorable when compared with ICG-assisted ILM peeling.

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Year:  2008        PMID: 18327134     DOI: 10.1097/IAE.0b013e31815ec2f1

Source DB:  PubMed          Journal:  Retina        ISSN: 0275-004X            Impact factor:   4.256


  12 in total

1.  Comparisons of focal macular electroretinograms after indocyanine green-, brilliant blue G-, or triamcinolone acetonide-assisted macular hole surgery.

Authors:  Shigeki Machida; Tomoharu Nishimura; Takayuki Ohzeki; Ken-Ichi Murai; Daijiro Kurosaka
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2016-09-07       Impact factor: 3.117

2.  Comparative evaluation of anatomical and functional outcomes using brilliant blue G versus triamcinolone assisted ILM peeling in macular hole surgery in Indian population.

Authors:  Atul Kumar; Varun Gogia; Vinit M Shah; Tapas C Nag
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-01-14       Impact factor: 3.117

3.  Internal limiting membrane peeling with different dyes in the surgery of idiopathic macular hole: a systematic review of literature and network Meta-analysis.

Authors:  Shan-Shan Li; Ran You; Min Li; Xiao-Xiao Guo; Lu Zhao; Yan-Ling Wang; Xi Chen
Journal:  Int J Ophthalmol       Date:  2019-12-18       Impact factor: 1.779

4.  Toxicity profiles of subretinal indocyanine green, Brilliant Blue G, and triamcinolone acetonide: a comparative study.

Authors:  Rasmus Ejstrup; M la Cour; S Heegaard; J F Kiilgaard
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-12-16       Impact factor: 3.117

5.  Comparisons of cone electroretinograms after indocyanine green-, brilliant blue G-, or triamcinolone acetonide-assisted macular hole surgery.

Authors:  Shigeki Machida; Yoshiharu Toba; Tomoharu Nishimura; Takayuki Ohzeki; Ken-ichi Murai; Daijiro Kurosaka
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-03-02       Impact factor: 3.117

Review 6.  Visualizing vitreous in vitrectomy by triamcinolone.

Authors:  Taiji Sakamoto; Tatsuro Ishibashi
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2009-06-20       Impact factor: 3.117

7.  Indocyanine green-assisted internal limiting membrane peeling in macular hole surgery: a meta-analysis.

Authors:  Yan Wu; Wei Zhu; Ding Xu; Yan-Hong Li; Jun Ba; Xiao-Long Zhang; Fang Wang; Jing Yu
Journal:  PLoS One       Date:  2012-11-07       Impact factor: 3.240

8.  Outcomes of 23-gauge pars plana vitrectomy and internal limiting membrane peeling with brilliant blue in macular hole.

Authors:  Huseyin Sanisoglu; Mehmet Sahin Sevim; Betul Aktas; Semra Sevim; Ahmet Nohutcu
Journal:  Clin Ophthalmol       Date:  2011-08-19

Review 9.  A Review of Surgical Outcomes and Advances for Macular Holes.

Authors:  Peng-Peng Zhao; Shuang Wang; Nan Liu; Zhi-Min Shu; Jin-Song Zhao
Journal:  J Ophthalmol       Date:  2018-04-18       Impact factor: 1.909

10.  Comparisons of retinal nerve fiber layer thickness after indocyanine green, brilliant blue g, or triamcinolone acetonide-assisted macular hole surgery.

Authors:  Yoshiharu Toba; Shigeki Machida; Daijiro Kurosaka
Journal:  J Ophthalmol       Date:  2014-05-19       Impact factor: 1.909

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