Literature DB >> 18293570

Leakage and scatter radiation from a double scattering based proton beamline.

M F Moyers1, E R Benton, A Ghebremedhin, G Coutrakon.   

Abstract

Proton beams offer several advantages over conventional radiation techniques for treating cancer and other diseases. These advantages might be negated if the leakage and scatter radiation from the beamline and patient are too large. Although the leakage and scatter radiation for the double scattering proton beamlines at the Loma Linda University Proton Treatment Facility were measured during the acceptance testing that occurred in the early 1990s, recent discussions in the radiotherapy community have prompted a reinvestigation of this contribution to the dose equivalent a patient receives. The dose and dose equivalent delivered to a large phantom patient outside a primary proton field were determined using five methods: simulations using Monte Carlo calculations, measurements with silver halide film, measurements with ionization chambers, measurements with rem meters, and measurements with CR-39 plastic nuclear track detectors. The Monte Carlo dose distribution was calculated in a coronal plane through the simulated patient that coincided with the central axis of the beam. Measurements with the ionization chambers, rem meters, and plastic nuclear track detectors were made at multiple locations within the same coronal plane. Measurements with the film were done in a plane perpendicular to the central axis of the beam and coincident with the surface of the phantom patient. In general, agreement between the five methods was good, but there were some differences. Measurements and simulations also tended to be in agreement with the original acceptance testing measurements and results from similar facilities published in the literature. Simulations illustrated that most of the neutrons entering the patient are produced in the final patient-specific aperture and precollimator just upstream of the aperture, not in the scattering system. These new results confirm that the dose equivalents received by patients outside the primary proton field from primary particles that leak through the nozzle are below the accepted standards for x-ray and electron beams. The total dose equivalent outside of the field is similar to that received by patients undergoing treatments with intensity modulated x-ray therapy. At the center of a patient for a whole course of treatment, the dose equivalent is comparable to that delivered by a single whole-body XCT scan.

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Year:  2008        PMID: 18293570     DOI: 10.1118/1.2805086

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  19 in total

1.  An analytic model of neutron ambient dose equivalent and equivalent dose for proton radiotherapy.

Authors:  Rui Zhang; Angélica Pérez-Andújar; Jonas D Fontenot; Phillip J Taddei; Wayne D Newhauser
Journal:  Phys Med Biol       Date:  2010-11-12       Impact factor: 3.609

2.  Assessment of out-of-field absorbed dose and equivalent dose in proton fields.

Authors:  Ben Clasie; Andrew Wroe; Hanne Kooy; Nicolas Depauw; Jay Flanz; Harald Paganetti; Anatoly Rosenfeld
Journal:  Med Phys       Date:  2010-01       Impact factor: 4.071

3.  Contribution to Neutron Fluence and Neutron Absorbed Dose from Double Scattering Proton Therapy System Components.

Authors:  A Pérez-Andújar; W D Newhauser; P M Deluca
Journal:  Nucl Technol       Date:  2009-01-01

4.  Monte Carlo and analytical model predictions of leakage neutron exposures from passively scattered proton therapy.

Authors:  Angélica Pérez-Andújar; Rui Zhang; Wayne Newhauser
Journal:  Med Phys       Date:  2013-12       Impact factor: 4.071

5.  Excessive applicator radiation leakage for a common therapeutic kilovoltage system.

Authors:  Brad Beeksma; Joerg Lehmann
Journal:  Br J Radiol       Date:  2018-11-15       Impact factor: 3.039

6.  Benchmark measurements and simulations of dose perturbations due to metallic spheres in proton beams.

Authors:  Wayne D Newhauser; Laura Rechner; Dragan Mirkovic; Pablo Yepes; Nicholas C Koch; Uwe Titt; Jonas D Fontenot; Rui Zhang
Journal:  Radiat Meas       Date:  2013-11-01       Impact factor: 1.898

7.  REDUCING STRAY RADIATION DOSE FOR A PEDIATRIC PATIENT RECEIVING PROTON CRANIOSPINAL IRRADIATION.

Authors:  Phillip J Taddei; Dragan Mirkovic; Jonas D Fontenot; Annelise Giebeler; Yuanshui Zheng; Uwe Titt; Shiao Woo; Wayne D Newhauser
Journal:  Nucl Technol       Date:  2009-10-01

Review 8.  Assessment of the risk for developing a second malignancy from scattered and secondary radiation in radiation therapy.

Authors:  Harald Paganetti
Journal:  Health Phys       Date:  2012-11       Impact factor: 1.316

9.  Reduction of the secondary neutron dose in passively scattered proton radiotherapy, using an optimized pre-collimator/collimator.

Authors:  David J Brenner; Carl D Elliston; Eric J Hall; Harald Paganetti
Journal:  Phys Med Biol       Date:  2009-09-24       Impact factor: 3.609

10.  Monte Carlo simulation of the neutron spectral fluence and dose equivalent for use in shielding a proton therapy vault.

Authors:  Yuanshui Zheng; Wayne Newhauser; Eric Klein; Daniel Low
Journal:  Phys Med Biol       Date:  2009-11-04       Impact factor: 3.609

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