Literature DB >> 20871789

Contribution to Neutron Fluence and Neutron Absorbed Dose from Double Scattering Proton Therapy System Components.

A Pérez-Andújar1, W D Newhauser, P M Deluca.   

Abstract

Proton therapy offers low integral dose and good tumor comformality in many deep-seated tumors. However, secondary particles generated during proton therapy, such as neutrons, are a concern, especially for passive scattering systems. In this type of system, the proton beam interacts with several components of the treatment nozzle that lie along the delivery path and can produce secondary neutrons. Neutron production along the beam's central axis in a double scattering passive system was examined using Monte Carlo simulations. Neutron fluence and energy distribution were determined downstream of the nozzle's major components at different radial distances from the central axis. In addition, the neutron absorbed dose per primary proton around the nozzle was investigated. Neutron fluence was highest immediately downstream of the range modulator wheel (RMW) but decreased as distance from the RMW increased. The nozzle's final collimator and snout also contributed to the production of high-energy neutrons. In fact, for the smallest treatment volume simulated, the neutron absorbed dose per proton at isocenter increased by a factor of 20 due to the snout presence when compared with a nozzle without a snout. The presented results can be used to design more effective local shielding components inside the treatment nozzle as well as to better understand the treatment room shielding requirements.

Entities:  

Year:  2009        PMID: 20871789      PMCID: PMC2943637     

Source DB:  PubMed          Journal:  Nucl Technol        ISSN: 0029-5450


  18 in total

1.  A treatment planning inter-comparison of proton and intensity modulated photon radiotherapy.

Authors:  A J Lomax; T Bortfeld; G Goitein; J Debus; C Dykstra; P A Tercier; P A Coucke; R O Mirimanoff
Journal:  Radiother Oncol       Date:  1999-06       Impact factor: 6.280

Review 2.  Potential gains using high-energy protons for therapy of malignant tumours.

Authors:  B Glimelius; U Isacsson; E Blomquist; E Grusell; B Jung; A Montelius
Journal:  Acta Oncol       Date:  1999       Impact factor: 4.089

3.  Virtual commissioning of a treatment planning system for proton therapy of ocular cancers.

Authors:  N Koch; W Newhauser
Journal:  Radiat Prot Dosimetry       Date:  2005       Impact factor: 0.972

4.  Design tools for proton therapy nozzles based on the double-scattering foil technique.

Authors:  J D Fontenot; W D Newhauser; U Titt
Journal:  Radiat Prot Dosimetry       Date:  2005       Impact factor: 0.972

5.  Monte Carlo investigation of collimator scatter of proton-therapy beams produced using the passive scattering method.

Authors:  Uwe Titt; Yuanshui Zheng; Oleg N Vassiliev; Wayne D Newhauser
Journal:  Phys Med Biol       Date:  2007-12-28       Impact factor: 3.609

6.  Radiological use of fast protons.

Authors:  R R WILSON
Journal:  Radiology       Date:  1946-11       Impact factor: 11.105

Review 7.  A review of proton beam radiation therapy.

Authors:  D W Miller
Journal:  Med Phys       Date:  1995-11       Impact factor: 4.071

8.  Monte Carlo simulation of a protontherapy platform devoted to ocular melanoma.

Authors:  J Hérault; N Iborra; B Serrano; P Chauvel
Journal:  Med Phys       Date:  2005-04       Impact factor: 4.071

9.  Neutron production from beam-modifying devices in a modern double scattering proton therapy beam delivery system.

Authors:  Angélica Pérez-Andújar; Wayne D Newhauser; Paul M Deluca
Journal:  Phys Med Biol       Date:  2009-01-16       Impact factor: 3.609

10.  Secondary neutron and photon dose in proton therapy.

Authors:  S Agosteo; C Birattari; M Caravaggio; M Silari; G Tosi
Journal:  Radiother Oncol       Date:  1998-09       Impact factor: 6.280

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