Literature DB >> 18260614

Physicochemical properties of antibacterial compounds: implications for drug discovery.

Rosemarie O'Shea1, Heinz E Moser.   

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Year:  2008        PMID: 18260614     DOI: 10.1021/jm700967e

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  161 in total

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2.  Defining desirable central nervous system drug space through the alignment of molecular properties, in vitro ADME, and safety attributes.

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4.  A community-based approach to new antibiotic discovery.

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Review 5.  Antibacterial drug discovery in the resistance era.

Authors:  Eric D Brown; Gerard D Wright
Journal:  Nature       Date:  2016-01-21       Impact factor: 49.962

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7.  Liquid crystalline bacterial outer membranes are critical for antibiotic susceptibility.

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8.  Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase.

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Journal:  Medchemcomm       Date:  2017-02-27       Impact factor: 3.597

9.  All signals lost.

Authors:  Kaelyn E Wilke; Erin E Carlson
Journal:  Sci Transl Med       Date:  2013-09-18       Impact factor: 17.956

10.  Design, synthesis, and biological evaluation of α-hydroxyacyl-AMS inhibitors of amino acid adenylation enzymes.

Authors:  Tony D Davis; Poornima Mohandas; Maria I Chiriac; Glennon V Bythrow; Luis E N Quadri; Derek S Tan
Journal:  Bioorg Med Chem Lett       Date:  2016-09-16       Impact factor: 2.823

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