Literature DB >> 18243310

Enhancing livestock through genetic engineering--recent advances and future prospects.

G Laible1.   

Abstract

Transgenic technology allows for the stable introduction of exogenous genetic information into livestock genomes. With its ability to enhance existing or introduce entirely novel characteristics at unprecedented magnitude and speed this emerging technology is expected to have a profound impact on the genetic improvement of livestock in the future. The continual advances in animal genomics towards the identification of genes that influence livestock production traits and impact on human health will increase its ability and versatility for the purposeful modification of livestock animals to enhance their welfare, produce superior quality food and biomedical products and reduce the environmental impact of farming. In contrast to biomedicine, which has so far been the main driver for this technology platform, the potential opportunities for animal agriculture are more challenging because of the greater demands on cost, efficiency, consumer acceptance and relative value of the product. While various transgenic concepts for the genetic improvement of livestock animals for agriculture are being evaluated the integration of this technology into practical farming systems remains some distance in the future.

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Year:  2008        PMID: 18243310     DOI: 10.1016/j.cimid.2007.11.012

Source DB:  PubMed          Journal:  Comp Immunol Microbiol Infect Dis        ISSN: 0147-9571            Impact factor:   2.268


  9 in total

1.  Welfare assessment in transgenic pigs expressing green fluorescent protein (GFP).

Authors:  Reinhard C Huber; Liliana Remuge; Ailsa Carlisle; Simon Lillico; Peter Sandøe; Dorte B Sørensen; C Bruce A Whitelaw; I Anna S Olsson
Journal:  Transgenic Res       Date:  2011-12-16       Impact factor: 2.788

2.  Genetic engineering of animals: ethical issues, including welfare concerns.

Authors:  Elisabeth H Ormandy; Julie Dale; Gilly Griffin
Journal:  Can Vet J       Date:  2011-05       Impact factor: 1.008

Review 3.  Genetically engineered livestock for agriculture: a generation after the first transgenic animal research conference.

Authors:  James D Murray; Elizabeth A Maga
Journal:  Transgenic Res       Date:  2016-01-28       Impact factor: 2.788

4.  Targeted microRNA expression in dairy cattle directs production of β-lactoglobulin-free, high-casein milk.

Authors:  Anower Jabed; Stefan Wagner; Judi McCracken; David N Wells; Goetz Laible
Journal:  Proc Natl Acad Sci U S A       Date:  2012-10-01       Impact factor: 11.205

5.  Development, Characterization, and Pluripotency Analysis of Buffalo (Bubalus bubalis) Embryonic Stem Cell Lines Derived from In Vitro-Fertilized, Hand-Guided Cloned, and Parthenogenetic Embryos.

Authors:  Syed Mohmad Shah; Neha Saini; Syma Ashraf; Mohammad Zandi; Radhey Sham Manik; Suresh Kumar Singla; Prabhat Palta; Manmohan Singh Chauhan
Journal:  Cell Reprogram       Date:  2015-07-13       Impact factor: 1.987

6.  Activation of GH signaling and GH-independent stimulation of growth in zebrafish by introduction of a constitutively activated GHR construct.

Authors:  A S Ishtiaq Ahmed; Feng Xiong; Shao-Chen Pang; Mu-Dan He; Michael J Waters; Zuo-Yan Zhu; Yong-Hua Sun
Journal:  Transgenic Res       Date:  2010-08-29       Impact factor: 2.788

7.  Comprehensive assessment of milk composition in transgenic cloned cattle.

Authors:  Ran Zhang; Chengdong Guo; Shunchao Sui; Tian Yu; Jianwu Wang; Ning Li
Journal:  PLoS One       Date:  2012-11-21       Impact factor: 3.240

8.  Expression of intracellular interferon-alpha confers antiviral properties in transfected bovine fetal fibroblasts and does not affect the full development of SCNT embryos.

Authors:  Dawei Yu; Shoufeng Zhang; Weihua Du; Jinxia Zhang; Zongxing Fan; Haisheng Hao; Yan Liu; Xueming Zhao; Tong Qin; Huabin Zhu
Journal:  PLoS One       Date:  2014-07-08       Impact factor: 3.240

9.  Induction of systemic IFITM3 expression does not effectively control foot-and-mouth disease viral infection in transgenic pigs.

Authors:  Huawei Zhang; Haixue Zheng; Ping Qian; Jinfang Xu; Xi Yang; Rui Zhou; Huanchun Chen; Xiangmin Li
Journal:  Vet Microbiol       Date:  2016-05-31       Impact factor: 3.293

  9 in total

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