Literature DB >> 18237143

Novel isocyanide-based three-component synthesis of 3,4-dihydroquinoxalin-2-amine derivatives.

Ahmad Shaabani1, Ali Maleki, Hamid Mofakham, Hamid Reza Khavasi.   

Abstract

Synthesis of a novel class of highly substituted 3,4-dihydroquinoxalin-2-amine derivatives including spirocyclic compounds from three-component condensation reaction of o-phenylenediamines, diverse carbonyl compounds, and isocyanides in the presence of a catalytic amount of p-toluenesulfonic acid in good to excellent yields at room temperature is described.

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Year:  2008        PMID： 18237143     DOI： 10.1021/cc7001777

Source DB:  PubMed          Journal:  J Comb Chem        ISSN： 1520-4766


  10 in total

Review 1.  Recent progress of isocyanide-based multicomponent reactions in Iran.

Authors:  Ahmad Shaabani; Ali Maleki; Ali Hossein Rezayan; Afshin Sarvary
Journal:  Mol Divers       Date:  2010-07-29       Impact factor: 2.943

2.  A novel one-pot pseudo-five-component condensation reaction towards bifunctional diazepine-tetrazole containing compounds: synthesis of 1H-tetrazolyl-1H-1,4-diazepine-2,3-dicarbonitriles and 1H-tetrazolyl-benzo[b][1,4]diazepines.

Authors:  Hamid Mofakham; Ahmad Shaabani; Sajjad Mousavifaraz; Fatemeh Hajishaabanha; Shabnam Shaabani; Seik Weng Ng
Journal:  Mol Divers       Date:  2012-05-17       Impact factor: 2.943

3.  Ammonium chloride-catalyzed green multicomponent synthesis of dihydropyrazine and tetrahydrodiazepine derivatives "on water".

Authors:  Ahmad Shaabani; Heshmatollah Sepahvand; Shima Ghasemi
Journal:  Mol Divers       Date:  2018-11-21       Impact factor: 2.943

4.  Synthesis and receptor profiling of Stemona alkaloid analogues reveal a potent class of sigma ligands.

Authors:  Kevin J Frankowski; Vincent Setola; Jon M Evans; Ben Neuenswander; Bryan L Roth; Jeffrey Aubé
Journal:  Proc Natl Acad Sci U S A       Date:  2011-02-28       Impact factor: 11.205

5.  A new one-pot three-component synthesis of 2,4-diamino-5H-chromeno[2,3-b]pyridine-3-carbonitrile derivatives.

Authors:  Ahmad Shaabani; Fatemeh Hajishaabanha; Hamid Mofakham; Ali Maleki
Journal:  Mol Divers       Date:  2009-05-16       Impact factor: 2.943

6.  A novel synthesis of highly substituted imidazo[1,5-a]pyrazine derivatives by 3-CR/2-CR sequence.

Authors:  Ahmad Shaabani; Ali Maleki; Hamid Mofakham
Journal:  Mol Divers       Date:  2008-11-21       Impact factor: 2.943

7.  Catalyst-free synthesis of novel 1,5-benzodiazepines and 3,4-dihydroquinoxalines using isocyanide-based one-pot, three- and four-component reactions.

Authors:  Reagan L Mohlala; E Mabel Coyanis; Manuel A Fernandes; Moira L Bode
Journal:  RSC Adv       Date:  2021-07-13       Impact factor: 4.036

8.  A novel class of extended pi-conjugated systems: one-pot synthesis of bis-3-aminoimidazo[1,2-a]pyridines, pyrimidines and pyrazines.

Authors:  Ahmad Shaabani; Ebrahim Soleimani; Ali Maleki; Jafar Moghimi-Rad
Journal:  Mol Divers       Date:  2008-12-02       Impact factor: 3.364

9.  Three-component coupling approach for the synthesis of diverse heterocycles utilizing reactive nitrilium trapping.

Authors:  András Váradi; Travis C Palmer; Paula R Notis; Gabriel N Redel-Traub; Daniel Afonin; Joan J Subrath; Gavril W Pasternak; Chunhua Hu; Indrajeet Sharma; Susruta Majumdar
Journal:  Org Lett       Date:  2014-02-28       Impact factor: 6.005

Review 10.  Isocyanide-Based Multicomponent Reactions for the Synthesis of Heterocycles.

Authors:  András Váradi; Travis C Palmer; Rebecca Notis Dardashti; Susruta Majumdar
Journal:  Molecules       Date:  2015-12-23       Impact factor: 4.411
  10 in total

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