Literature DB >> 19449111

A new one-pot three-component synthesis of 2,4-diamino-5H-chromeno[2,3-b]pyridine-3-carbonitrile derivatives.

Ahmad Shaabani1, Fatemeh Hajishaabanha, Hamid Mofakham, Ali Maleki.   

Abstract

In this study, a three-component one-pot synthesis of new 2,4-diamino-5H-chromeno[2,3-b]pyridine-3-carbonitriles derived from 2-amino-1,1,3-tricyanopropene, salicylic aldehydes and secondary cyclic amines is reported. The reaction is conducted in ethanol at ambient temperature in good-to-excellent yields.

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Year:  2009        PMID: 19449111     DOI: 10.1007/s11030-009-9152-x

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  15 in total

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Journal:  Bioorg Med Chem Lett       Date:  2005-03-15       Impact factor: 2.823

2.  One-step synthesis of heterocyclic privileged medicinal scaffolds by a multicomponent reaction of malononitrile with aldehydes and thiols.

Authors:  Nikolai M Evdokimov; Artem S Kireev; Andrey A Yakovenko; Mikhail Yu Antipin; Igor V Magedov; Alexander Kornienko
Journal:  J Org Chem       Date:  2007-04-05       Impact factor: 4.354

3.  A novel isocyanide-based three-component reaction: synthesis of highly substituted 1,6-dihydropyrazine-2,3-dicarbonitrile derivatives.

Authors:  Ahmad Shaabani; Ali Maleki; Jafar Moghimi-Rad
Journal:  J Org Chem       Date:  2007-07-04       Impact factor: 4.354

4.  Design, synthesis and antiproliferative activity of some new azapyranoxanthenone aminoderivatives.

Authors:  George Kolokythas; Nicole Pouli; Panagiotis Marakos; Harris Pratsinis; Dimitris Kletsas
Journal:  Eur J Med Chem       Date:  2005-11-21       Impact factor: 6.514

5.  NAD+-dependent DNA Ligase (Rv3014c) from Mycobacterium tuberculosis. Crystal structure of the adenylation domain and identification of novel inhibitors.

Authors:  Sandeep Kumar Srivastava; Rama Pati Tripathi; Ravishankar Ramachandran
Journal:  J Biol Chem       Date:  2005-05-17       Impact factor: 5.157

6.  Convenient one-step synthesis of a medicinally relevant benzopyranopyridine system.

Authors:  Nikolai M Evdokimov; Artem S Kireev; Andrey A Yakovenko; Mikhail Yu Antipin; Igor V Magedov; Alexander Kornienko
Journal:  Tetrahedron Lett       Date:  2006-12-25       Impact factor: 2.415

7.  Novel isocyanide-based three-component synthesis of 3,4-dihydroquinoxalin-2-amine derivatives.

Authors:  Ahmad Shaabani; Ali Maleki; Hamid Mofakham; Hamid Reza Khavasi
Journal:  J Comb Chem       Date:  2008-02-01

8.  Synthesis of the metabolites and degradation products of 2-amino-7-isopropyl-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3- carboxylic acid (Amoxanox).

Authors:  K Ukawa; T Ishiguro; H Kuriki; A Nohara
Journal:  Chem Pharm Bull (Tokyo)       Date:  1985-10       Impact factor: 1.645

9.  Novel multicomponent one-pot synthesis of tetrahydro-1H-1,5-benzodiazepine-2-carboxamide derivatives.

Authors:  Ahmad Shaabani; Ali Maleki; Hamid Mofakham
Journal:  J Comb Chem       Date:  2008-06-14

10.  Cancer chemopreventive effect of phenothiazines and related tri-heterocyclic analogues in the 12-O-tetradecanoylphorbol-13-acetate promoted Epstein-Barr virus early antigen activation and the mouse skin two-stage carcinogenesis models.

Authors:  Magnus A Azuine; Harukuni Tokuda; Junko Takayasu; Fumio Enjyo; Teruo Mukainaka; Takao Konoshima; Hoyoku Nishino; Govind J Kapadia
Journal:  Pharmacol Res       Date:  2004-02       Impact factor: 7.658

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  1 in total

Review 1.  Malononitrile dimer as a privileged reactant in design and skeletal diverse synthesis of heterocyclic motifs.

Authors:  Ahmad Shaabani; Seyyed Emad Hooshmand
Journal:  Mol Divers       Date:  2018-01-03       Impact factor: 2.943

  1 in total

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