BACKGROUND: Different imaging modalities have been explored for assessment of left ventricular (LV) dyssynchrony. Gated myocardial perfusion single photon emission computed tomography (GMPS) with phase analysis is a reliable technique to quantify LV dyssynchrony and predict response to cardiac resynchronization therapy. OBJECTIVE: Real-time 3-dimensional echocardiography (RT3DE) is a novel imaging technique that provides a LV systolic dyssynchrony index, based on regional volumetric changes as a function of time and calculated as the SD of time to minimum systolic volume of 16 standard myocardial segments expressed in percentage of cardiac cycle. The aim of this study was to compare LV dyssynchrony evaluated with GMPS with LV dyssynchrony assessed with RT3DE. METHODS: The study population consisted of 40 patients with heart failure who underwent both GMPS and RT3DE. RESULTS: Good correlations between LV dyssynchrony assessed with RT3DE and GMPS were demonstrated (r = 0.76 for histogram bandwidth, r = 0.80 for phase SD, P < .0001). Patients with substantial LV dyssynchrony on GMPS (defined as > or = 135 degrees for histogram bandwidth and > or = 43 degrees for phase SD) had significantly higher LV systolic dyssynchrony index than patients without substantial LV dyssynchrony. CONCLUSIONS: The good correlations between LV dyssynchrony assessed with GMPS and with RT3DE provide further support for the use of RT3DE for reliable assessment of LV dyssynchrony.
BACKGROUND: Different imaging modalities have been explored for assessment of left ventricular (LV) dyssynchrony. Gated myocardial perfusion single photon emission computed tomography (GMPS) with phase analysis is a reliable technique to quantify LV dyssynchrony and predict response to cardiac resynchronization therapy. OBJECTIVE: Real-time 3-dimensional echocardiography (RT3DE) is a novel imaging technique that provides a LV systolic dyssynchrony index, based on regional volumetric changes as a function of time and calculated as the SD of time to minimum systolic volume of 16 standard myocardial segments expressed in percentage of cardiac cycle. The aim of this study was to compare LV dyssynchrony evaluated with GMPS with LV dyssynchrony assessed with RT3DE. METHODS: The study population consisted of 40 patients with heart failure who underwent both GMPS and RT3DE. RESULTS: Good correlations between LV dyssynchrony assessed with RT3DE and GMPS were demonstrated (r = 0.76 for histogram bandwidth, r = 0.80 for phase SD, P < .0001). Patients with substantial LV dyssynchrony on GMPS (defined as > or = 135 degrees for histogram bandwidth and > or = 43 degrees for phase SD) had significantly higher LV systolic dyssynchrony index than patients without substantial LV dyssynchrony. CONCLUSIONS: The good correlations between LV dyssynchrony assessed with GMPS and with RT3DE provide further support for the use of RT3DE for reliable assessment of LV dyssynchrony.
Authors: Harald P Kühl; Marcus Schreckenberg; Dierk Rulands; Markus Katoh; Wolfgang Schäfer; Georg Schummers; Arno Bücker; Peter Hanrath; Andreas Franke Journal: J Am Coll Cardiol Date: 2004-06-02 Impact factor: 24.094
Authors: Nikolay P Nikitin; Cristina Constantin; Poay Huan Loh; Justin Ghosh; Elena I Lukaschuk; Anna Bennett; Sarah Hurren; Farqad Alamgir; Andrew L Clark; John G F Cleland Journal: Eur J Echocardiogr Date: 2006-08-17
Authors: Ji Chen; Ernest V Garcia; Russell D Folks; C David Cooke; Tracy L Faber; E Lindsey Tauxe; Ami E Iskandrian Journal: J Nucl Cardiol Date: 2005 Nov-Dec Impact factor: 5.952
Authors: G Germano; H Kiat; P B Kavanagh; M Moriel; M Mazzanti; H T Su; K F Van Train; D S Berman Journal: J Nucl Med Date: 1995-11 Impact factor: 10.057
Authors: Jos J M Westenberg; Hildo J Lamb; Rob J van der Geest; Gabe B Bleeker; Eduard R Holman; Martin J Schalij; Albert de Roos; Ernst E van der Wall; Johan H C Reiber; Jeroen J Bax Journal: J Am Coll Cardiol Date: 2006-04-24 Impact factor: 24.094
Authors: M G Levine; C C McGill; A W Ahlberg; M P White; S Giri; B Shareef; D Waters; G V Heller Journal: Am J Cardiol Date: 1999-01-01 Impact factor: 2.778
Authors: Jeroen J Bax; Gabe B Bleeker; Thomas H Marwick; Sander G Molhoek; Eric Boersma; Paul Steendijk; Ernst E van der Wall; Martin J Schalij Journal: J Am Coll Cardiol Date: 2004-11-02 Impact factor: 24.094
Authors: Wael AlJaroudi; M Chadi Alraies; Frank DiFilippo; Richard C Brunken; Manuel D Cerqueira; Wael A Jaber Journal: Eur J Nucl Med Mol Imaging Date: 2012-01-05 Impact factor: 9.236
Authors: Ji Chen; Andreas P Kalogeropoulos; Liudmila Verdes; Javed Butler; Ernest V Garcia Journal: J Nucl Cardiol Date: 2011-01-13 Impact factor: 5.952
Authors: Ji Chen; Mark J Boogers; Mark M Boogers; Jeroen J Bax; Prem Soman; Ernest V Garcia Journal: Curr Cardiol Rep Date: 2010-03 Impact factor: 2.931