Literature DB >> 18196388

Obesity is a major risk factor for prosthetic infection after primary hip arthroplasty.

Michelle M Dowsey1, Peter F M Choong.   

Abstract

UNLABELLED: The incidence of obesity and the number of hip arthroplasties being performed in Australia each year are increasing. Although uncommon, periprosthetic infection after surgery can have a devastating effect on patient outcomes. We therefore asked whether obesity correlated with periprosthetic infection after primary hip arthroplasty. We further asked whether variables such as patient comorbidities, operative time, blood transfusions, use of drains, and cementation practices correlated with periprosthetic infection. We hypothesized obesity was an independent risk factor for the development of acute periprosthetic infection after primary hip arthroplasty. We reviewed 1207 consecutive primary hip arthroplasties separating patients into four weight groups, normal, overweight, obese, and morbidly obese, and compared for incidence of periprosthetic infection between the groups. We observed a considerably higher infection rate in obese patients; the correlation was independent of patient comorbidities such as diabetes and cardiovascular disease. We also observed a correlation between infection rates and using a posterior approach in obese patients. The incidence of periprosthetic infection was not influenced by operative time, transfusion requirements, use of drains, and cementation practices. In this series, obesity was an independent risk factor for acute periprosthetic infection after primary hip arthroplasty. LEVEL OF EVIDENCE: Level II, prognostic study.

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Mesh:

Year:  2008        PMID: 18196388      PMCID: PMC2505299          DOI: 10.1007/s11999-007-0016-3

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  35 in total

1.  Hip abductor strength following total hip arthroplasty: a prospective comparison of the posterior and lateral approach in 100 patients.

Authors:  N D Downing; D I Clark; J W Hutchinson; K Colclough; P W Howard
Journal:  Acta Orthop Scand       Date:  2001-06

2.  Total hip replacement due to osteoarthritis: the importance of age, obesity, and other modifiable risk factors.

Authors:  Elizabeth W Karlson; Lisa A Mandl; Gideon N Aweh; Oliver Sangha; Matthew H Liang; Francine Grodstein
Journal:  Am J Med       Date:  2003-02-01       Impact factor: 4.965

3.  Changes in body mass index following primary elective total hip arthroplasty. Correlation with outcome at 2 years.

Authors:  Shiv A Jain; Richard T Roach; John Travlos
Journal:  Acta Orthop Belg       Date:  2003-10       Impact factor: 0.500

4.  Defining the relationship between obesity and total joint arthroplasty.

Authors:  B Stickles; L Phillips; W T Brox; B Owens; W L Lanzer
Journal:  Obes Res       Date:  2001-03

5.  Predictors of wound infection in hip and knee joint replacement: results from a 20 year surveillance program.

Authors:  Khaled Saleh; Mary Olson; Scott Resig; Boris Bershadsky; Mike Kuskowski; Terence Gioe; Harry Robinson; Richard Schmidt; Edward McElfresh
Journal:  J Orthop Res       Date:  2002-05       Impact factor: 3.494

6.  An evaluation of patients' quality of life before, 6 weeks and 6 months after total hip replacement surgery.

Authors:  S Knutsson; I B Engberg
Journal:  J Adv Nurs       Date:  1999-12       Impact factor: 3.187

7.  Orthopedic Surgery Transfusion Hemoglobin European Overview (OSTHEO) study: blood management in elective knee and hip arthroplasty in Europe.

Authors:  Nadia Rosencher; Hans E M Kerkkamp; G Macheras; L M Munuera; G Menichella; David M Barton; Saskia Cremers; Ivo L Abraham
Journal:  Transfusion       Date:  2003-04       Impact factor: 3.157

8.  Risk factors for clinically relevant pulmonary embolism and deep venous thrombosis in patients undergoing primary hip or knee arthroplasty.

Authors:  Carlos B Mantilla; Terese T Horlocker; Darrell R Schroeder; Daniel J Berry; David L Brown
Journal:  Anesthesiology       Date:  2003-09       Impact factor: 7.892

9.  Risk factors associated with acute hip prosthetic joint infections and outcome of treatment with a rifampinbased regimen.

Authors:  Peter F M Choong; Michelle M Dowsey; Derek Carr; John Daffy; Peter Stanley
Journal:  Acta Orthop       Date:  2007-12       Impact factor: 3.717

10.  Body mass indices in patients with disabling hip osteoarthritis.

Authors:  Ray Marks; John P Allegrante
Journal:  Arthritis Res       Date:  2001-11-01
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  52 in total

1.  Operating room traffic is a major concern during total joint arthroplasty.

Authors:  Pedram Panahi; Mitchell Stroh; David S Casper; Javad Parvizi; Matthew S Austin
Journal:  Clin Orthop Relat Res       Date:  2012-10       Impact factor: 4.176

2.  Meta-analysis shows that obesity may be a significant risk factor for prosthetic joint infections.

Authors:  Zhongxi Ma; Fengjin Guo; Jun Qi; Wei Xiang; Jinming Zhang
Journal:  Int Orthop       Date:  2015-08-15       Impact factor: 3.075

Review 3.  Risk factors for periprosthetic joint infection following primary total hip or knee arthroplasty: a meta-analysis.

Authors:  Lingde Kong; Junming Cao; Yingze Zhang; Wenyuan Ding; Yong Shen
Journal:  Int Wound J       Date:  2016-07-10       Impact factor: 3.315

Review 4.  What does irritable bowel syndrome share with non-alcoholic fatty liver disease?

Authors:  Antonella Scalera; Matteo Nicola Dario Di Minno; Giovanni Tarantino
Journal:  World J Gastroenterol       Date:  2013-09-07       Impact factor: 5.742

Review 5.  Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE).

Authors:  Daniel J Raiten; Fayrouz A Sakr Ashour; A Catharine Ross; Simin N Meydani; Harry D Dawson; Charles B Stephensen; Bernard J Brabin; Parminder S Suchdev; Ben van Ommen
Journal:  J Nutr       Date:  2015-04-01       Impact factor: 4.798

Review 6.  [Total hip arthroplasty in overweight osteoarthritis patients].

Authors:  M Stiehler; J Goronzy; K-P Günther
Journal:  Orthopade       Date:  2015-07       Impact factor: 1.087

7.  Do claims-based comorbidities adequately capture case mix for surgical site infections?

Authors:  Hilal Maradit Kremers; Laura W Lewallen; Brian D Lahr; Tad M Mabry; James M Steckelberg; Daniel J Berry; Arlen D Hanssen; Elie F Berbari; Douglas R Osmon
Journal:  Clin Orthop Relat Res       Date:  2014-12-06       Impact factor: 4.176

8.  Passive immunization with anti-glucosaminidase monoclonal antibodies protects mice from implant-associated osteomyelitis by mediating opsonophagocytosis of Staphylococcus aureus megaclusters.

Authors:  John J Varrone; Karen L de Mesy Bentley; Sheila N Bello-Irizarry; Kohei Nishitani; Sarah Mack; Joshua G Hunter; Stephen L Kates; John L Daiss; Edward M Schwarz
Journal:  J Orthop Res       Date:  2014-07-03       Impact factor: 3.494

9.  Complication rates after hip or knee arthroplasty in morbidly obese patients.

Authors:  Richard J Friedman; Susanne Hess; Scott D Berkowitz; Martin Homering
Journal:  Clin Orthop Relat Res       Date:  2013-05-14       Impact factor: 4.176

Review 10.  Clinical practice. Infection associated with prosthetic joints.

Authors:  Jose L Del Pozo; Robin Patel
Journal:  N Engl J Med       Date:  2009-08-20       Impact factor: 91.245

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