Zhongxi Ma1, Fengjin Guo2, Jun Qi1, Wei Xiang1, Jinming Zhang1. 1. Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jiefang Road, Wuhan, 430030, Hubei Province, China. 2. Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jiefang Road, Wuhan, 430030, Hubei Province, China. 82099179@microsci.com.
Abstract
PURPOSE: Our aim was to evaluate the association between the different degree of obesity and prosthetic joint infections (PJIs) after total hip replacement (THR) by performing a meta-analysis. METHODS: PubMed, Cochrane library and Embase databases up to May, 2014 were retrieved for identifying relevant studies. Relative risk (RR) and their 95 % confidence intervals (CIs) were used as effect sizes. RESULTS: A total of 15 articles were included in this meta-analysis. The overall analyses showed that the risk of PJIs in the BMI ≥ 30 group and in BMI ≥ 40 group were significantly higher than that in the BMI < 30 group. As well, the prospective pooled results showed that overweight and obesity could significantly increase the incidence of PJIs. CONCLUSIONS: Our meta-analysis indicates that all of obesity levels can significantly increase the risk of PJIs. However, further studies with more strict design are need in the future.
PURPOSE: Our aim was to evaluate the association between the different degree of obesity and prosthetic joint infections (PJIs) after total hip replacement (THR) by performing a meta-analysis. METHODS: PubMed, Cochrane library and Embase databases up to May, 2014 were retrieved for identifying relevant studies. Relative risk (RR) and their 95 % confidence intervals (CIs) were used as effect sizes. RESULTS: A total of 15 articles were included in this meta-analysis. The overall analyses showed that the risk of PJIs in the BMI ≥ 30 group and in BMI ≥ 40 group were significantly higher than that in the BMI < 30 group. As well, the prospective pooled results showed that overweight and obesity could significantly increase the incidence of PJIs. CONCLUSIONS: Our meta-analysis indicates that all of obesity levels can significantly increase the risk of PJIs. However, further studies with more strict design are need in the future.
Entities:
Keywords:
Body mass index; Meta-analysis; Prosthetic joint infections; Total hip replacement
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