Literature DB >> 12038624

Predictors of wound infection in hip and knee joint replacement: results from a 20 year surveillance program.

Khaled Saleh1, Mary Olson, Scott Resig, Boris Bershadsky, Mike Kuskowski, Terence Gioe, Harry Robinson, Richard Schmidt, Edward McElfresh.   

Abstract

BACKGROUND: Deep wound infection (DWI) in total knee (TKA) and total hip (THA) arthroplasty has been shown to highly correlate with superficial surgical site infection (SSSI). Although several studies have reported hospital factors that predispose to SSSI, patient factors have not been clearly elucidated.
METHODS: All patients undergoing TKA (n = 1181) and THA (n = 1124) surgery during the period 1977-1995 at our institution were observed at the end of a 30-day post-operative period. Thirty-three patients that developed SSSI during this period constituted the study group. The control group was composed of 64 matched subjects that did not develop SSSI. A chart review was applied to abstract DWI cases during the first 18 post-operative months for the study group and for an average of 6.7 years for the control group (range 5-18.2 years). Potential risk factors for SSSI were used as predictors of SSSI in a logistic regression analysis.
RESULTS: During the 18-month observation period 19 out of the 33 study subjects (58%) developed DWI. No DWI was registered in the control group (the difference was significant, p < 0.0001). Of the nine pre-operative, five intra-operative, and five postoperative factors examined, only hematoma formation (odds ratio = 11.8; p = 0.001) and days of post-operative drainage (odds ratio = 1.32; p = 0.01) were significant predictors of SSSI. The cases consumed more health care resources at all stages of the medical process.
CONCLUSIONS: Our results (1) confirm the strong correlation between the probability of developing DWI and SSSI; (2) indicate that hematoma formation and persistent post-operative drainage increase the risk of SSSI. We hypothesize that post-operative monitoring of patients for hematoma and persistent drainage enables earlier intervention that may lower the risk of developing SSSI and subsequent DWI.

Entities:  

Mesh:

Year:  2002        PMID: 12038624     DOI: 10.1016/S0736-0266(01)00153-X

Source DB:  PubMed          Journal:  J Orthop Res        ISSN: 0736-0266            Impact factor:   3.494


  91 in total

1.  [Prevention of wound infections: basic measures].

Authors:  K Lewalter; S W Lemmen
Journal:  Orthopade       Date:  2012-01       Impact factor: 1.087

2.  Knee arthroplasty and bleeding: when to remove drainages.

Authors:  Oscar Ares; Roberto Seijas; Alberto Hernandez; Enric Castellet; Andrea Sallent
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-03-28       Impact factor: 4.342

Review 3.  Wound complications in total knee arthroplasty. Which flap is to be used? With or without retention of prosthesis?

Authors:  Alfredo Schiavone Panni; Michele Vasso; Simone Cerciello; Marzia Salgarello
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-12-15       Impact factor: 4.342

4.  [Prevention of postoperative wound infections].

Authors:  K Engelke; K J Oldhafer
Journal:  Chirurg       Date:  2010-06       Impact factor: 0.955

5.  Pasteurella multocida infection of a total knee arthroplasty after a "dog lick".

Authors:  B Heym; F Jouve; M Lemoal; A Veil-Picard; A Lortat-Jacob; M H Nicolas-Chanoine
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2006-02-09       Impact factor: 4.342

6.  Procrastination of wound drainage and malnutrition affect the outcome of joint arthroplasty.

Authors:  Fereidoon M Jaberi; Javad Parvizi; C Thomas Haytmanek; Ashish Joshi; James Purtill
Journal:  Clin Orthop Relat Res       Date:  2008-04-11       Impact factor: 4.176

7.  Does adding antibiotics to cement reduce the need for early revision in total knee arthroplasty?

Authors:  Eric Bohm; Naisu Zhu; Jing Gu; Nicole de Guia; Cassandra Linton; Tammy Anderson; David Paton; Michael Dunbar
Journal:  Clin Orthop Relat Res       Date:  2014-01       Impact factor: 4.176

Review 8.  An evidence-based review of enhanced recovery interventions in knee replacement surgery.

Authors:  M S Ibrahim; S Alazzawi; I Nizam; F S Haddad
Journal:  Ann R Coll Surg Engl       Date:  2013-09       Impact factor: 1.891

9.  A superficial swab culture is useful for microbiologic diagnosis in acute prosthetic joint infections.

Authors:  Jordi Cuñé; Alex Soriano; Juan C Martínez; Sebastián García; Josep Mensa
Journal:  Clin Orthop Relat Res       Date:  2008-10-11       Impact factor: 4.176

10.  Negative pressure wound therapy is associated with resolution of incisional drainage in most wounds after hip arthroplasty.

Authors:  Erik Hansen; Joel B Durinka; James A Costanzo; Matthew S Austin; Gregory K Deirmengian
Journal:  Clin Orthop Relat Res       Date:  2013-10       Impact factor: 4.176

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