Literature DB >> 18056274

In vitro activities of voriconazole, itraconazole, and terbinafine alone or in combination against Pythium insidiosum isolates from Brazil.

Juliana S Argenta1, Janio M Santurio, Sydney H Alves, Daniela I B Pereira, Ayrton S Cavalheiro, Andréia Spanamberg, Laerte Ferreiro.   

Abstract

We evaluated the in vitro activities of voriconazole, itraconazole, and terbinafine against 30 clinical isolates of Pythium insidiosum using a checkerboard macrodilution method. The combined activity of terbinafine plus itraconazole or plus voriconazole was synergic against 17% of the strains. Antagonism was not observed.

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Year:  2007        PMID: 18056274      PMCID: PMC2224725          DOI: 10.1128/AAC.01075-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  14 in total

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  15 in total

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3.  In vitro synergism observed with azithromycin, clarithromycin, minocycline, or tigecycline in association with antifungal agents against Pythium insidiosum.

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10.  In Vitro Synergism between Azithromycin or Terbinafine and Topical Antimicrobial Agents against Pythium insidiosum.

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