Literature DB >> 18041491

Automatic analysis of single-channel sleep EEG: validation in healthy individuals.

Christian Berthomier1, Xavier Drouot, Maria Herman-Stoïca, Pierre Berthomier, Jacques Prado, Djibril Bokar-Thire, Odile Benoit, Jérémie Mattout, Marie-Pia d'Ortho.   

Abstract

STUDY
OBJECTIVE: To assess the performance of automatic sleep scoring software (ASEEGA) based on a single EEG channel comparatively with manual scoring (2 experts) of conventional full polysomnograms.
DESIGN: Polysomnograms from 15 healthy individuals were scored by 2 independent experts using conventional R&K rules. The results were compared to those of ASEEGA scoring on an epoch-by-epoch basis.
SETTING: Sleep laboratory in the physiology department of a teaching hospital. PARTICIPANTS: Fifteen healthy volunteers. MEASUREMENTS AND
RESULTS: The epoch-by-epoch comparison was based on classifying into 2 states (wake/sleep), 3 states (wake/REM/ NREM), 4 states (wake/REM/stages 1-2/SWS), or 5 states (wake/REM/ stage 1/stage 2/SWS). The obtained overall agreements, as quantified by the kappa coefficient, were 0.82, 0.81, 0.75, and 0.72, respectively. Furthermore, obtained agreements between ASEEGA and the expert consensual scoring were 96.0%, 92.1%, 84.9%, and 82.9%, respectively. Finally, when classifying into 5 states, the sensitivity and positive predictive value of ASEEGA regarding wakefulness were 82.5% and 89.7%, respectively. Similarly, sensitivity and positive predictive value regarding REM state were 83.0% and 89.1%.
CONCLUSIONS: Our results establish the face validity and convergent validity of ASEEGA for single-channel sleep analysis in healthy individuals. ASEEGA appears as a good candidate for diagnostic aid and automatic ambulant scoring.

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Year:  2007        PMID: 18041491      PMCID: PMC2082104          DOI: 10.1093/sleep/30.11.1587

Source DB:  PubMed          Journal:  Sleep        ISSN: 0161-8105            Impact factor:   5.849


  33 in total

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