Literature DB >> 18020967

Critical evaluation of 1H NMR metabonomics of serum as a methodology for disease risk assessment and diagnostics.

Mika Ala-Korpela1.   

Abstract

This review focuses on (i) the current status of 1H NMR spectroscopy to quantify lipoprotein subclasses directly from serum or plasma, and (ii) the applications of 1H NMR metabonomics of serum in biomedicine. Related to both themes, experimental and data analysis methodologies are discussed together with the biochemical rationales. Particular emphasis is placed on the concepts of risk assessment and diagnostics in relation to the potential clinical role of 1H NMR metabonomics; recent applications in the area of coronary heart disease and diabetes are addressed in more detail.

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Year:  2008        PMID： 18020967     DOI： 10.1515/CCLM.2008.006

Source DB:  PubMed          Journal:  Clin Chem Lab Med        ISSN： 1434-6621            Impact factor:   3.694


  32 in total

1.  Optimization of a direct analysis in real time/time-of-flight mass spectrometry method for rapid serum metabolomic fingerprinting.

Authors:  Manshui Zhou; John F McDonald; Facundo M Fernández
Journal:  J Am Soc Mass Spectrom       Date:  2009-09-17       Impact factor: 3.109

Review 2.  The emerging field of quantitative blood metabolomics for biomarker discovery in critical illnesses.

Authors:  Natalie J Serkova; Theodore J Standiford; Kathleen A Stringer
Journal:  Am J Respir Crit Care Med       Date:  2011-06-16       Impact factor: 21.405

Review 3.  Advances in NMR-based biofluid analysis and metabolite profiling.

Authors:  Shucha Zhang; G A Nagana Gowda; Tao Ye; Daniel Raftery
Journal:  Analyst       Date:  2010-04-09       Impact factor: 4.616

4.  Metabolic consequences of sepsis-induced acute lung injury revealed by plasma ¹H-nuclear magnetic resonance quantitative metabolomics and computational analysis.

Authors:  Kathleen A Stringer; Natalie J Serkova; Alla Karnovsky; Kenneth Guire; Robert Paine; Theodore J Standiford
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2010-10-01       Impact factor: 5.464

5.  Untargeted LC-MS metabolomics of bronchoalveolar lavage fluid differentiates acute respiratory distress syndrome from health.

Authors:  Charles R Evans; Alla Karnovsky; Melissa A Kovach; Theodore J Standiford; Charles F Burant; Kathleen A Stringer
Journal:  J Proteome Res       Date:  2013-12-09       Impact factor: 4.466

Review 6.  Metabolomics-based methods for early disease diagnostics.

Authors:  G A Nagana Gowda; Shucha Zhang; Haiwei Gu; Vincent Asiago; Narasimhamurthy Shanaiah; Daniel Raftery
Journal:  Expert Rev Mol Diagn       Date:  2008-09       Impact factor: 5.225

Review 7.  Metabolomics as a diagnostic tool in gastroenterology.

Authors:  Vicky De Preter; Kristin Verbeke
Journal:  World J Gastrointest Pharmacol Ther       Date:  2013-11-06

8.  Large-scale human metabolic phenotyping and molecular epidemiological studies via 1H NMR spectroscopy of urine: investigation of borate preservation.

Authors:  Leon M Smith; Anthony D Maher; Elizabeth J Want; Paul Elliott; Jeremiah Stamler; Geoffrey E Hawkes; Elaine Holmes; John C Lindon; Jeremy K Nicholson
Journal:  Anal Chem       Date:  2009-06-15       Impact factor: 6.986

9.  Mild cognitive impairment associates with concurrent decreases in serum cholesterol and cholesterol-related lipoprotein subclasses.

Authors:  T Tukiainen; P Jylänki; V P Mäkinen; O Gröhn; M Hallikainen; H Soininen; M Kivipelto; K Kaski; P H Groop; M J Savolainen; T Pirttilä; P Soininen; M Ala-Korpela
Journal:  J Nutr Health Aging       Date:  2012-07       Impact factor: 4.075

10.  Association of height and pubertal timing with lipoprotein subclass profile: exploring the role of genetic and environmental effects.

Authors:  Aline Jelenkovic; Leonie H Bogl; Richard J Rose; Antti J Kangas; Pasi Soininen; Mika Ala-Korpela; Jaakko Kaprio; Karri Silventoinen
Journal:  Am J Hum Biol       Date:  2013-05-04       Impact factor: 1.937
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