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Literature DB >> 20379603

Advances in NMR-based biofluid analysis and metabolite profiling.

Shucha Zhang¹, G A Nagana Gowda, Tao Ye, Daniel Raftery.

Abstract

Significant improvements in NMR technology and methods have propelled NMR studies to play an important role in a rapidly expanding number of applications involving the profiling of metabolites in biofluids. This review discusses recent technical advances in NMR spectroscopy based metabolite profiling methods, data processing and analysis over the last three years.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Biomarkers

Year: 2010 PMID： 20379603 PMCID： PMC4720135 DOI： 10.1039/c000091d

Source DB: PubMed Journal: Analyst ISSN： 0003-2654 Impact factor: 4.616

113 in total

1. Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets.

Authors: Olivier Cloarec; Marc-Emmanuel Dumas; Andrew Craig; Richard H Barton; Johan Trygg; Jane Hudson; Christine Blancher; Dominique Gauguier; John C Lindon; Elaine Holmes; Jeremy Nicholson
Journal: Anal Chem Date: 2005-03-01 Impact factor: 6.986

2. SOGGY: solvent-optimized double gradient spectroscopy for water suppression. A comparison with some existing techniques.

Authors: Bao D Nguyen; Xi Meng; Kevin J Donovan; A J Shaka
Journal: J Magn Reson Date: 2006-11-27 Impact factor: 2.229

Review 3. Environmental metabolomics: a SWOT analysis (strengths, weaknesses, opportunities, and threats).

Authors: Marion G Miller
Journal: J Proteome Res Date: 2007-02 Impact factor: 4.466

Review 4. Metabolomics-based systems biology and personalized medicine: moving towards n = 1 clinical trials?

Authors: Jan van der Greef; Thomas Hankemeier; Robert N McBurney
Journal: Pharmacogenomics Date: 2006-10 Impact factor: 2.533

5. Two-dimensional DOSY experiment with Excitation Sculpting water suppression for the analysis of natural and biological media.

Authors: Stéphane Balayssac; Marc-André Delsuc; Véronique Gilard; Yann Prigent; Myriam Malet-Martino
Journal: J Magn Reson Date: 2008-09-30 Impact factor: 2.229

6. The human cerebrospinal fluid metabolome.

Authors: David S Wishart; Michael J Lewis; Joshua A Morrissey; Mitchel D Flegel; Kevin Jeroncic; Yeping Xiong; Dean Cheng; Roman Eisner; Bijaya Gautam; Dan Tzur; Summit Sawhney; Fiona Bamforth; Russ Greiner; Liang Li
Journal: J Chromatogr B Analyt Technol Biomed Life Sci Date: 2008-05-08 Impact factor: 3.205

7. Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice.

Authors: Marc-Emmanuel Dumas; Richard H Barton; Ayo Toye; Olivier Cloarec; Christine Blancher; Alice Rothwell; Jane Fearnside; Roger Tatoud; Véronique Blanc; John C Lindon; Steve C Mitchell; Elaine Holmes; Mark I McCarthy; James Scott; Dominique Gauguier; Jeremy K Nicholson
Journal: Proc Natl Acad Sci U S A Date: 2006-08-08 Impact factor: 11.205

8. Monitoring diet effects via biofluids and their implications for metabolomics studies.

Authors: Haiwei Gu; Huanwen Chen; Zhengzheng Pan; Ayanna U Jackson; Nari Talaty; Bowei Xi; Candice Kissinger; Chester Duda; Doug Mann; Daniel Raftery; R Graham Cooks
Journal: Anal Chem Date: 2007-01-01 Impact factor: 6.986

9. Principal component analysis of urine metabolites detected by NMR and DESI-MS in patients with inborn errors of metabolism.

Authors: Zhengzheng Pan; Haiwei Gu; Nari Talaty; Huanwen Chen; Narasimhamurthy Shanaiah; Bryan E Hainline; R Graham Cooks; Daniel Raftery
Journal: Anal Bioanal Chem Date: 2006-07-05 Impact factor: 4.142

Advances in NMR-based biofluid analysis and metabolite profiling.

1. Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets.

2. SOGGY: solvent-optimized double gradient spectroscopy for water suppression. A comparison with some existing techniques.

Review 3. Environmental metabolomics: a SWOT analysis (strengths, weaknesses, opportunities, and threats).

Review 4. Metabolomics-based systems biology and personalized medicine: moving towards n = 1 clinical trials?

5. Two-dimensional DOSY experiment with Excitation Sculpting water suppression for the analysis of natural and biological media.

6. The human cerebrospinal fluid metabolome.

7. Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice.

8. Monitoring diet effects via biofluids and their implications for metabolomics studies.

9. Principal component analysis of urine metabolites detected by NMR and DESI-MS in patients with inborn errors of metabolism.

10. Metabolite profiling of human amniotic fluid by hyphenated nuclear magnetic resonance spectroscopy.

1. Use of optimized 1D TOCSY NMR for improved quantitation and metabolomic analysis of biofluids.

2. Metabolomic analysis of the effects of polychlorinated biphenyls in nonalcoholic fatty liver disease.

Review 3. Postgenomics diagnostics: metabolomics approaches to human blood profiling.

Review 4. Metabolomic signature of brain cancer.

Review 5. Role of Metabolomics in Traumatic Brain Injury Research.

Review 6. Can NMR solve some significant challenges in metabolomics?

7. Bayesian deconvolution and quantification of metabolites in complex 1D NMR spectra using BATMAN.

8. Quantitative analysis of urea in human urine and serum by 1H nuclear magnetic resonance.

Review 9. Metabolomics in rheumatic diseases: desperately seeking biomarkers.

10. Metabolic Profiling of Green Tea Treatments in Zucker Diabetic Rats Using ¹H NMR.