Literature DB >> 18007461

Syntheses of quinazoline-2,4-dione alkaloids and analogues from Mexican Zanthoxylum species.

I A Rivero1, K Espinoza, R Somanathan.   

Abstract

Quinazolinone and quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties. In this paper we report the synthesis of ten quinazolinediones. The previous isolation of two of these compounds, namely 1-methyl-3-(2'-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2'-(4'- methoxyphenyl)ethyl]-lH,3H-quinazoline-2,4-dione, from the seed husks of Mexican Zanthoxylum species has been reported.

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Year:  2004        PMID： 18007461      PMCID： PMC6147351          DOI： 10.3390/90700609

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  12 in total

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4.  New sedative and hypotensive 3-substituted 2,4(1H,3H)-quinazolinediones.

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8.  UV-Guided isolation of alantrypinone, a novel Penicillium alkaloid.

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  5 in total

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2.  Synthesis and evaluation of 1-cyclopropyl-2-thioalkyl-8-methoxy fluoroquinolones.

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4.  I2/TBHP mediated domino synthesis of 2-(2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-N-aryl/alkyl benzamides and evaluation of their anticancer and docking studies.

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5.  Alkylation of 2,4-(1H,3H)-quinazolinediones with dialkyl carbonates under microwave irradiations.

Authors:  Ignacio Alfredo Rivero; Leticia Guerrero; Karla Alejandra Espinoza; Martha Cecilia Meza; Jesús Ramón Rodríguez
Journal:  Molecules       Date:  2009-05-20       Impact factor: 4.411
  5 in total

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