Literature DB >> 7517439

Spiroquinazoline, a novel substance P inhibitor with a new carbon skeleton, isolated from Aspergillus flavipes.

C J Barrow1, H H Sun.   

Abstract

A novel substance P inhibitor, spiroquinazoline [1], was isolated from the fungus Aspergillus flavipes, which was originally obtained from soil. The structure of 1 was determined by analysis of spectroscopic data and 1 was shown to contain a new carbon skeleton containing a spiro-carbon center. Also isolated from the same culture extract were the new natural product, benzodiazepiedione [3], and the known compounds, acyl aszonalenin [4], N-benzoyl-L-phenylalaninol, and seven diketopiperazines.

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Year:  1994        PMID: 7517439     DOI: 10.1021/np50106a005

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  15 in total

1.  Syntheses of Highly Functionalized δ,γ-Unsaturated-α-Amino Acids.

Authors:  Siyuan Chen; Robert M Williams
Journal:  Tetrahedron       Date:  2006-12-11       Impact factor: 2.457

2.  Secondary metabolites produced by Microbacterium sp. LGMB471 with antifungal activity against the phytopathogen Phyllosticta citricarpa.

Authors:  Daiani Cristina Savi; Khaled A Shaaban; Francielly M W Gos; Jon S Thorson; Chirlei Glienke; Jürgen Rohr
Journal:  Folia Microbiol (Praha)       Date:  2018-12-18       Impact factor: 2.099

3.  Optimized production and isolation of antibacterial agent from marine Aspergillus flavipes against Vibrio harveyi.

Authors:  Lei Guo; Cong Wang
Journal:  3 Biotech       Date:  2017-10-30       Impact factor: 2.406

4.  Enzymatic processing of fumiquinazoline F: a tandem oxidative-acylation strategy for the generation of multicyclic scaffolds in fungal indole alkaloid biosynthesis.

Authors:  Brian D Ames; Xinyu Liu; Christopher T Walsh
Journal:  Biochemistry       Date:  2010-09-08       Impact factor: 3.162

5.  Syntheses of quinazoline-2,4-dione alkaloids and analogues from Mexican Zanthoxylum species.

Authors:  I A Rivero; K Espinoza; R Somanathan
Journal:  Molecules       Date:  2004-06-30       Impact factor: 4.411

6.  Aniquinazolines A-D, four new quinazolinone alkaloids from marine-derived endophytic fungus Aspergillus nidulans.

Authors:  Chun-Yan An; Xiao-Ming Li; Chun-Shun Li; Ming-Hui Wang; Gang-Ming Xu; Bin-Gui Wang
Journal:  Mar Drugs       Date:  2013-07-23       Impact factor: 5.118

7.  New meroterpenoids from the endophytic fungus Aspergillus flavipes AIL8 derived from the mangrove plant Acanthus ilicifolius.

Authors:  Zhi-Qiang Bai; Xiuping Lin; Junfeng Wang; Xuefeng Zhou; Juan Liu; Bin Yang; Xianwen Yang; Shengrong Liao; Lishu Wang; Yonghong Liu
Journal:  Mar Drugs       Date:  2015-01-07       Impact factor: 5.118

8.  Different Culture Metabolites of the Red Sea Fungus Fusarium equiseti Optimize the Inhibition of Hepatitis C Virus NS3/4A Protease (HCV PR).

Authors:  Usama W Hawas; Radwan Al-Farawati; Lamia T Abou El-Kassem; Adnan J Turki
Journal:  Mar Drugs       Date:  2016-10-20       Impact factor: 5.118

9.  Bioactive secondary metabolites from a new terrestrial Streptomyces sp. TN262.

Authors:  Lobna Elleuch; Mohamed Shaaban; Slim Smaoui; Lotfi Mellouli; Ines Karray-Rebai; Lilia Fourati-Ben Fguira; Khaled A Shaaban; Hartmut Laatsch
Journal:  Appl Biochem Biotechnol       Date:  2009-10-20       Impact factor: 2.926

10.  Transcriptional and Proteomic Profiling of Aspergillus flavipes in Response to Sulfur Starvation.

Authors:  Ashraf S A El-Sayed; Marwa A Yassin; Gul Shad Ali
Journal:  PLoS One       Date:  2015-12-03       Impact factor: 3.240

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