Literature DB >> 17990255

Reassignment of the structure of the antibiotic A53868 reveals an unusual amino dehydrophosphonic acid.

John T Whitteck1, Weijuan Ni, Benjamin M Griffin, Andrew C Eliot, Paul M Thomas, Neil L Kelleher, William W Metcalf, Wilfred A van der Donk.   

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Year:  2007        PMID: 17990255     DOI: 10.1002/anie.200703810

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  11 in total

1.  Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis.

Authors:  Jin-Hee Lee; Brian Bae; Michael Kuemin; Benjamin T Circello; William W Metcalf; Satish K Nair; Wilfred A van der Donk
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-27       Impact factor: 11.205

2.  Structure-activity relationships of the phosphonate antibiotic dehydrophos.

Authors:  Michael Kuemin; Wilfred A van der Donk
Journal:  Chem Commun (Camb)       Date:  2010-09-27       Impact factor: 6.222

3.  The antibiotic dehydrophos is converted to a toxic pyruvate analog by peptide bond cleavage in Salmonella enterica.

Authors:  Benjamin T Circello; Charles G Miller; Jin-Hee Lee; Wilfred A van der Donk; William W Metcalf
Journal:  Antimicrob Agents Chemother       Date:  2011-05-02       Impact factor: 5.191

Review 4.  Structure and mechanism of enzymes involved in biosynthesis and breakdown of the phosphonates fosfomycin, dehydrophos, and phosphinothricin.

Authors:  Satish K Nair; Wilfred A van der Donk
Journal:  Arch Biochem Biophys       Date:  2010-09-18       Impact factor: 4.013

5.  Molecular cloning and heterologous expression of the dehydrophos biosynthetic gene cluster.

Authors:  Benjamin T Circello; Andrew C Eliot; Jin-Hee Lee; Wilfred A van der Donk; William W Metcalf
Journal:  Chem Biol       Date:  2010-04-23

6.  Revisiting the biosynthesis of dehydrophos reveals a tRNA-dependent pathway.

Authors:  Despina J Bougioukou; Subha Mukherjee; Wilfred A van der Donk
Journal:  Proc Natl Acad Sci U S A       Date:  2013-06-17       Impact factor: 11.205

Review 7.  Phosphonate biosynthesis and catabolism: a treasure trove of unusual enzymology.

Authors:  Spencer C Peck; Wilfred A van der Donk
Journal:  Curr Opin Chem Biol       Date:  2013-07-17       Impact factor: 8.822

8.  Biosynthesis of 2-hydroxyethylphosphonate, an unexpected intermediate common to multiple phosphonate biosynthetic pathways.

Authors:  Zengyi Shao; Joshua A V Blodgett; Benjamin T Circello; Andrew C Eliot; Ryan Woodyer; Gongyong Li; Wilfred A van der Donk; William W Metcalf; Huimin Zhao
Journal:  J Biol Chem       Date:  2008-06-10       Impact factor: 5.157

Review 9.  Biosynthesis of phosphonic and phosphinic acid natural products.

Authors:  William W Metcalf; Wilfred A van der Donk
Journal:  Annu Rev Biochem       Date:  2009       Impact factor: 23.643

Review 10.  Recent examples of α-ketoglutarate-dependent mononuclear non-haem iron enzymes in natural product biosyntheses.

Authors:  Shu-Shan Gao; Nathchar Naowarojna; Ronghai Cheng; Xueting Liu; Pinghua Liu
Journal:  Nat Prod Rep       Date:  2018-08-15       Impact factor: 13.423

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