Literature DB >> 17827303

The deoxycytidine pathway for thymidylate synthesis in Escherichia coli.

Bernard Weiss1.   

Abstract

When thymidylate production is diminished by a mutation affecting dCTP deaminase, Escherichia coli is known to use an alternate pathway involving deoxycytidine as an intermediate. The pathway requires the gene for any of three nucleoside diphosphate kinases (ndk, pykA, or pykF) and the gene for a 5'-nucleotidase (yfbR).

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Year:  2007        PMID: 17827303      PMCID: PMC2168750          DOI: 10.1128/JB.00461-07

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  27 in total

1.  An efficient recombination system for chromosome engineering in Escherichia coli.

Authors:  D Yu; H M Ellis; E C Lee; N A Jenkins; N G Copeland; D L Court
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

2.  YjjG, a dUMP phosphatase, is critical for thymine utilization by Escherichia coli K-12.

Authors:  Bernard Weiss
Journal:  J Bacteriol       Date:  2006-12-22       Impact factor: 3.490

3.  Altered deoxyribonucleotide pools in P2 eductants of Escherichia coli K-12 due to deletion of the dcd gene.

Authors:  J Neuhard; E Thomassen
Journal:  J Bacteriol       Date:  1976-05       Impact factor: 3.490

Review 4.  Pedigrees of some mutant strains of Escherichia coli K-12.

Authors:  B J Bachmann
Journal:  Bacteriol Rev       Date:  1972-12

5.  Nucleoside diphosphokinase of Salmonella typhimurium.

Authors:  C L Ginther; J L Ingraham
Journal:  J Biol Chem       Date:  1974-06-10       Impact factor: 5.157

6.  Orf135 from Escherichia coli Is a Nudix hydrolase specific for CTP, dCTP, and 5-methyl-dCTP.

Authors:  S F O'Handley; C A Dunn; M J Bessman
Journal:  J Biol Chem       Date:  2000-10-26       Impact factor: 5.157

7.  Thermodynamics of the pyruvate kinase reaction and the reversal of glycolysis in heart and skeletal muscle.

Authors:  Geoffrey P Dobson; Sam Hitchins; Walter E Teague
Journal:  J Biol Chem       Date:  2002-05-01       Impact factor: 5.157

8.  Salmonella typhimurium mutants defective in cytidine monophosphate kinase (cmk).

Authors:  C F Beck; J Neuhard; E Thomassen; J L Ingraham; E Kleker
Journal:  J Bacteriol       Date:  1974-12       Impact factor: 3.490

9.  Massive accumulation of phosphatidic acid in conditionally lethal CDP-diglyceride synthetase mutants and cytidine auxotrophs of Escherichia coli.

Authors:  B R Ganong; C R Raetz
Journal:  J Biol Chem       Date:  1982-01-10       Impact factor: 5.157

10.  Deoxycytidine triphosphate deaminase: characterization of an Escherichia coli mutant deficient in the enzyme.

Authors:  G A O'Donovan; G Edlin; J A Fuchs; J Neuhard; E Thomassen
Journal:  J Bacteriol       Date:  1971-02       Impact factor: 3.490

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  11 in total

1.  The dgt gene of Escherichia coli facilitates thymine utilization in thymine-requiring strains.

Authors:  Mark Itsko; Roel M Schaaper
Journal:  Mol Microbiol       Date:  2011-07-12       Impact factor: 3.501

2.  Deoxycytidine deaminase-deficient Escherichia coli strains display acute sensitivity to cytidine, adenosine, and guanosine and increased sensitivity to a range of antibiotics, including vancomycin.

Authors:  Tina Manzhu Kang; Jessica Yuan; Alice Zhou; Casey Beppler; Jeffrey H Miller
Journal:  J Bacteriol       Date:  2014-03-14       Impact factor: 3.490

3.  Metabolic genes on conjugative plasmids are highly prevalent in Escherichia coli and can protect against antibiotic treatment.

Authors:  Alana Palomino; Danya Gewurz; Lela DeVine; Ujana Zajmi; Jenifer Moralez; Fatima Abu-Rumman; Robert P Smith; Allison J Lopatkin
Journal:  ISME J       Date:  2022-10-19       Impact factor: 11.217

4.  Structural insight into the mechanism of substrate specificity and catalytic activity of an HD-domain phosphohydrolase: the 5'-deoxyribonucleotidase YfbR from Escherichia coli.

Authors:  Matthew D Zimmerman; Michael Proudfoot; Alexander Yakunin; Wladek Minor
Journal:  J Mol Biol       Date:  2008-03-04       Impact factor: 5.469

5.  The phtC-phtD locus equips Legionella pneumophila for thymidine salvage and replication in macrophages.

Authors:  Maris V Fonseca; John-Demian Sauer; Sebastien Crepin; Brenda Byrne; Michele S Swanson
Journal:  Infect Immun       Date:  2013-12-02       Impact factor: 3.441

6.  Nucleotide parasitism by Simkania negevensis (Chlamydiae).

Authors:  Silvia Knab; Tanja M Mushak; Stephan Schmitz-Esser; Matthias Horn; Ilka Haferkamp
Journal:  J Bacteriol       Date:  2010-10-22       Impact factor: 3.490

7.  Evolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems.

Authors:  Lakshminarayan M Iyer; Dapeng Zhang; Igor B Rogozin; L Aravind
Journal:  Nucleic Acids Res       Date:  2011-09-03       Impact factor: 16.971

8.  Deoxycytidine production by a metabolically engineered Escherichia coli strain.

Authors:  Jin-Sook Kim; Bong-Seong Koo; Hyung-Hwan Hyun; Hyeon-Cheol Lee
Journal:  Microb Cell Fact       Date:  2015-07-07       Impact factor: 5.328

9.  An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations.

Authors:  Marcos H de Moraes; FoSheng Hsu; Dean Huang; Dustin E Bosch; Jun Zeng; Matthew C Radey; Noah Simon; Hannah E Ledvina; Jacob P Frick; Paul A Wiggins; S Brook Peterson; Joseph D Mougous
Journal:  Elife       Date:  2021-01-15       Impact factor: 8.713

10.  The Escherichia coli Cryptic Prophage Protein YfdR Binds to DnaA and Initiation of Chromosomal Replication Is Inhibited by Overexpression of the Gene Cluster yfdQ-yfdR-yfdS-yfdT.

Authors:  Yasunori Noguchi; Tsutomu Katayama
Journal:  Front Microbiol       Date:  2016-03-03       Impact factor: 5.640

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