Literature DB >> 17189366

YjjG, a dUMP phosphatase, is critical for thymine utilization by Escherichia coli K-12.

Bernard Weiss1.   

Abstract

Exogenous thymine must be converted to thymidine to enable a thyA (thymidylate synthase) mutant to grow. The deoxyribose in the thymidine comes from dUMP, which must first be dephosphorylated. The nucleotidase YjjG is critical for this step. A yjjG thyA mutant cannot use thymine for growth on a glucose minimal medium.

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Year:  2006        PMID： 17189366      PMCID： PMC1855703          DOI： 10.1128/JB.01645-06

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  13 in total

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