Literature DB >> 5541540

Deoxycytidine triphosphate deaminase: characterization of an Escherichia coli mutant deficient in the enzyme.

G A O'Donovan, G Edlin, J A Fuchs, J Neuhard, E Thomassen.   

Abstract

A mutant of Escherichia coli, previously shown to contain abnormal nucleoside triphosphate pools, was found to be defective in its ability to synthesize thymidine nucleotides. The defect is not in the enzyme thymidylate synthetase but in deoxycytidine triphosphate deaminase, an enzyme that supplies deoxyuridine monophosphate, the substrate for thymidylate synthetase.

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Year:  1971        PMID： 5541540      PMCID： PMC248447          DOI： 10.1128/jb.105.2.666-672.1971

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  22 in total

1.  Release of repressor control of ribonucleotide reductase by thymine starvation.

Authors:  C Biswas; J Hardy; W S Beck
Journal:  J Biol Chem       Date:  1965-09       Impact factor: 5.157

2.  Mutants of Salmonella typhimurium requiring cytidine for growth.

Authors:  J Neuhard; J Ingraham
Journal:  J Bacteriol       Date:  1968-06       Impact factor: 3.490

3.  Significance of ribonucleotide reduction in the biosynthesis of deoxyribonucleotides in Escherichia coli.

Authors:  O Karlström; A Larsson
Journal:  Eur J Biochem       Date:  1967-12

4.  Thymidine breakdown and thymine uptake in different mutants of Escherichia coli.

Authors:  A Munch-Petersen
Journal:  Biochim Biophys Acta       Date:  1967-06-20

5.  Enzymatic synthesis of deoxyribonucleotides. X. Reduction of purine ribonucleotides; allosteric behavior and substrate specificity of the enzyme system from Escherichia coli B.

Authors:  A Larsson; P Reichard
Journal:  J Biol Chem       Date:  1966-06-10       Impact factor: 5.157

6.  Enzymatic synthesis of deoxyribonucleotides. IX. Allosteric effects in the reduction of pyrimidine ribonucleotides by the ribonucleoside diphosphate reductase system of Escherichia coli.

Authors:  A Larsson; P Reichard
Journal:  J Biol Chem       Date:  1966-06-10       Impact factor: 5.157

7.  A new assay of thymidylate synthetase activity based on the release of tritium from deoxyuridylate-5-3-H.

Authors:  M I Lomax; G R Greenberg
Journal:  J Biol Chem       Date:  1967-01-10       Impact factor: 5.157

8.  A rapid assay for thymidylate synthetase.

Authors:  H O Kammen
Journal:  Anal Biochem       Date:  1966-12       Impact factor: 3.365

9.  Studies on the acid-soluble nucleotide pool in thymine-requiring mutants of Escherichia coli during thymine starvation. II. Changes in the amounts of deoxycytidine triphosphate and deoxyadenosine triphosphate in Escherichia coli 15 T-A-U.

Authors:  J Neuhard; A Munch-Petersen
Journal:  Biochim Biophys Acta       Date:  1966-01-18

10.  Mutant bacteria showing efficient utilization of thymidine.

Authors:  W L Fangman; A Novick
Journal:  J Bacteriol       Date:  1966-06       Impact factor: 3.490
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  33 in total

1.  Escherichia coli mutants deficient in deoxyuridine triphosphatase.

Authors:  S J Hochhauser; B Weiss
Journal:  J Bacteriol       Date:  1978-04       Impact factor: 3.490

2.  Altered deoxyribonucleotide pools in P2 eductants of Escherichia coli K-12 due to deletion of the dcd gene.

Authors:  J Neuhard; E Thomassen
Journal:  J Bacteriol       Date:  1976-05       Impact factor: 3.490

3.  The deoxycytidine pathway for thymidylate synthesis in Escherichia coli.

Authors:  Bernard Weiss
Journal:  J Bacteriol       Date:  2007-09-07       Impact factor: 3.490

4.  Chloroviruses encode a bifunctional dCMP-dCTP deaminase that produces two key intermediates in dTTP formation.

Authors:  Yuanzheng Zhang; Frank Maley; Gladys F Maley; Garry Duncan; David D Dunigan; James L Van Etten
Journal:  J Virol       Date:  2007-05-02       Impact factor: 5.103

5.  Genetic requirements for sensitivity of bacteriophage t7 to dideoxythymidine.

Authors:  Ngoc Q Tran; Stanley Tabor; Charles C Richardson
Journal:  J Bacteriol       Date:  2014-05-23       Impact factor: 3.490

Review 6.  Linkage map of Escherichia coli K-12, edition 10: the traditional map.

Authors:  M K Berlyn
Journal:  Microbiol Mol Biol Rev       Date:  1998-09       Impact factor: 11.056

7.  Thymidine-requiring mutants of Salmonella typhimurium that are defective in deoxyuridine 5'-phosphate synthesis.

Authors:  C F Beck; J Neuhard; E Thomassen
Journal:  J Bacteriol       Date:  1977-01       Impact factor: 3.490

8.  Isolation of a Saccharomyces cerevisiae mutant strain deficient in deoxycytidylate deaminase activity and partial characterization of the enzyme.

Authors:  E M McIntosh; R H Haynes
Journal:  J Bacteriol       Date:  1984-05       Impact factor: 3.490

9.  Mapping of nrdA and nrdB in Escherichia coli K-12.

Authors:  J A Fuchs; H O Karlström
Journal:  J Bacteriol       Date:  1976-12       Impact factor: 3.490

10.  Degree of participation of exogenous thymidine in the overall deoxyribonucleic acid synthesis in Escherichia coli.

Authors:  D Rosenbaum-Oliver; S Zamenhof
Journal:  J Bacteriol       Date:  1972-05       Impact factor: 3.490
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