Literature DB >> 17805717

Mechanism of lipoxidase reaction. I. Specificity of hydroperoxidation of linoleic acid.

A Dolev1, W K Rohwedder, H J Dutton.   

Abstract

Linoleate hydroperoxides from autoxidation of methyl linoleate and from lipoxidase oxidation of linoleic acid are compared. Data indicate an equal amount of methyl 9- and 13-hydroperoxyoctadecadienoate produced by autoxidation of methyl linoleate, and the exclusive formation of 13-hydroperoxyoctadeca-9,11-dienoic acid from the incubation of lipoxidase with linoleic acid. As a result of these findings, a specific mechanism for the reaction of lipoxidase with linoleic acid is postulated.

Entities:  

Year:  1967        PMID: 17805717     DOI: 10.1007/BF02531996

Source DB:  PubMed          Journal:  Lipids        ISSN: 0024-4201            Impact factor:   1.880


  8 in total

1.  Linoleic acid and trilinolein as substrates for soybean lipoxidase (s).

Authors:  R B KOCH; B STERN; C G FERRARI
Journal:  Arch Biochem Biophys       Date:  1958-11       Impact factor: 4.013

2.  Induction period in the lipoxidase-catalyzed oxidation of linoleic acid and its abolition by substrate peroxide.

Authors:  J L HAINING; B AXELROD
Journal:  J Biol Chem       Date:  1958-05       Impact factor: 5.157

3.  Coupled oxidation of carotene and linoleate catalyzed by lipoxidase.

Authors:  H L TOOKEY; R G WILSON; R L LOHMAR; H J DUTTON
Journal:  J Biol Chem       Date:  1958-01       Impact factor: 5.157

4.  Autoxidation of linoleic acid.

Authors:  S BERGSTROM
Journal:  Nature       Date:  1945-12-15       Impact factor: 49.962

5.  Spectrophotometric studies of the oxidation of fats; coupled oxidation of carotene.

Authors:  R T HOLMAN
Journal:  Arch Biochem       Date:  1949-03

6.  On the specificity of the lipoxidase catalyzed oxygenation of unsaturated fatty acids.

Authors:  M Hamberg; B Samuelsson
Journal:  Biochem Biophys Res Commun       Date:  1965-12-21       Impact factor: 3.575

7.  Quantitative separation of methyl 9-hydroxystearate from methyl 13-hydroxystearate by column chromatography on Silica gel.

Authors:  A Dolev; W K Rohwedder; H J Dutton
Journal:  Lipids       Date:  1966-05       Impact factor: 1.880

8.  Preparation of pure methyl esters by counter double current distribution.

Authors:  C R Scholfield; R O Butterfield; H J Dutton
Journal:  Lipids       Date:  1966-05       Impact factor: 1.880

  8 in total
  16 in total

1.  Pentane from thermal decomposition of lipoxidase-derived products.

Authors:  C D Evans; G R List; A Dolev; D G McConnell; R L Hoffmann
Journal:  Lipids       Date:  1967-09       Impact factor: 1.880

2.  A simplified gas chromatographic procedure for analysis of lipoxygenase reaction products.

Authors:  A J St Angelo; H P Dupuy; R L Ory
Journal:  Lipids       Date:  1972-12       Impact factor: 1.880

3.  The isolation and specificity of alfalfa lipoxygenase.

Authors:  C C Chang; W J Esselman; C O Clagett
Journal:  Lipids       Date:  1971-02       Impact factor: 1.880

4.  Reaction of lipoxidase with polyenoic acids in marine oils.

Authors:  J L Beare-Rogers; R G Ackman
Journal:  Lipids       Date:  1969-11       Impact factor: 1.880

5.  Specificity of flaxseed lipoxidase.

Authors:  D C Zimmerman; B A Vick
Journal:  Lipids       Date:  1970-04       Impact factor: 1.880

6.  The deposition of polyunsaturated fatty acids in the rat fed partially hydrogenated vegetable oil.

Authors:  J L Beare-Rogers
Journal:  J Am Oil Chem Soc       Date:  1970-12       Impact factor: 1.849

7.  Precursors of alk-2,4-dienals in autoxidized lard.

Authors:  W I Kimoto; A M Gaddis
Journal:  J Am Oil Chem Soc       Date:  1969-08       Impact factor: 1.849

8.  Hydroperoxide isomerase: a new enzyme of lipid metabolism.

Authors:  D C Zimmerman; B A Vick
Journal:  Plant Physiol       Date:  1970-09       Impact factor: 8.340

9.  Isolation of a pure isomer of linoleic acid hydroperoxide.

Authors:  H W Gardner
Journal:  Lipids       Date:  1975-04       Impact factor: 1.880

10.  Dependence of Escherichia coli hyperbaric oxygen toxicity on the lipid acyl chain composition.

Authors:  J B Harley; G M Santangelo; H Rasmussen; H Goldfine
Journal:  J Bacteriol       Date:  1978-06       Impact factor: 3.490

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