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Literature DB >> 17665911

Supercharging proteins can impart unusual resilience.

Michael S Lawrence¹, Kevin J Phillips, David R Liu.

Abstract

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Year: 2007 PMID： 17665911 PMCID： PMC2820565 DOI： 10.1021/ja071641y

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

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18 in total

1. Removal of surface charge-charge interactions from ubiquitin leaves the protein folded and very stable.

Authors: Vakhtang V Loladze; George I Makhatadze
Journal: Protein Sci Date: 2002-01 Impact factor: 6.725

2. Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases.

Authors: Amol P Pawar; Kateri F Dubay; Jesús Zurdo; Fabrizio Chiti; Michele Vendruscolo; Christopher M Dobson
Journal: J Mol Biol Date: 2005-07-08 Impact factor: 5.469

3. Rational design of aggregation-resistant bioactive peptides: reengineering human calcitonin.

Authors: Susan B Fowler; Stephen Poon; Roman Muff; Fabrizio Chiti; Christopher M Dobson; Jesús Zurdo
Journal: Proc Natl Acad Sci U S A Date: 2005-07-08 Impact factor: 11.205

4. Protein stability and surface electrostatics: a charged relationship.

Authors: Samantha S Strickler; Alexey V Gribenko; Alexander V Gribenko; Timothy R Keiffer; Jessica Tomlinson; Tracey Reihle; Vakhtang V Loladze; George I Makhatadze
Journal: Biochemistry Date: 2006-03-07 Impact factor: 3.162

Review 5. Why are proteins charged? Networks of charge-charge interactions in proteins measured by charge ladders and capillary electrophoresis.

Authors: Irina Gitlin; Jeffrey D Carbeck; George M Whitesides
Journal: Angew Chem Int Ed Engl Date: 2006-05-05 Impact factor: 15.336

6. Mechanism of coupled folding and binding of an intrinsically disordered protein.

Authors: Kenji Sugase; H Jane Dyson; Peter E Wright
Journal: Nature Date: 2007-05-23 Impact factor: 49.962

7. Eliminating positively charged lysine epsilon-NH3+ groups on the surface of carbonic anhydrase has no significant influence on its folding from sodium dodecyl sulfate.

Authors: Katherine L Gudiksen; Irina Gitlin; Jerry Yang; Adam R Urbach; Demetri T Moustakas; George M Whitesides
Journal: J Am Chem Soc Date: 2005-04-06 Impact factor: 15.419

8. The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins.

Authors: Zsuzsanna Dosztányi; Veronika Csizmók; Péter Tompa; István Simon
Journal: J Mol Biol Date: 2005-04-08 Impact factor: 5.469

Review 9. Therapeutic approaches to protein-misfolding diseases.

Authors: Fred E Cohen; Jeffery W Kelly
Journal: Nature Date: 2003-12-18 Impact factor: 49.962

10. CHEMICAL AND PHYSICAL BEHAVIOR OF CASEIN SOLUTIONS.

Authors: J Loeb
Journal: J Gen Physiol Date: 1921-03-20 Impact factor: 4.086

170 in total

1. Directed evolution of an ultrastable carbonic anhydrase for highly efficient carbon capture from flue gas.

Authors: Oscar Alvizo; Luan J Nguyen; Christopher K Savile; Jamie A Bresson; Satish L Lakhapatri; Earl O P Solis; Richard J Fox; James M Broering; Michael R Benoit; Sabrina A Zimmerman; Scott J Novick; Jack Liang; James J Lalonde
Journal: Proc Natl Acad Sci U S A Date: 2014-11-03 Impact factor: 11.205

Supercharging proteins can impart unusual resilience.

1. Removal of surface charge-charge interactions from ubiquitin leaves the protein folded and very stable.

2. Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases.

3. Rational design of aggregation-resistant bioactive peptides: reengineering human calcitonin.

4. Protein stability and surface electrostatics: a charged relationship.

Review 5. Why are proteins charged? Networks of charge-charge interactions in proteins measured by charge ladders and capillary electrophoresis.

6. Mechanism of coupled folding and binding of an intrinsically disordered protein.

7. Eliminating positively charged lysine epsilon-NH3+ groups on the surface of carbonic anhydrase has no significant influence on its folding from sodium dodecyl sulfate.

8. The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins.

Review 9. Therapeutic approaches to protein-misfolding diseases.

10. CHEMICAL AND PHYSICAL BEHAVIOR OF CASEIN SOLUTIONS.

1. Directed evolution of an ultrastable carbonic anhydrase for highly efficient carbon capture from flue gas.

2. General strategy for the generation of human antibody variable domains with increased aggregation resistance.

3. pK(a) values for the unfolded state under native conditions explain the pH-dependent stability of PGB1.

4. Solubilization of a membrane protein by combinatorial supercharging.

5. Boosting protein stability with the computational design of β-sheet surfaces.

6. The E3 ubiquitin ligase UBE3C enhances proteasome processivity by ubiquitinating partially proteolyzed substrates.

7. Arresting amyloid with coulomb's law: acetylation of ALS-linked SOD1 by aspirin impedes aggregation.

8. Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation.

9. Folding study of Venus reveals a strong ion dependence of its yellow fluorescence under mildly acidic conditions.

10. Protein delivery using Cys2-His2 zinc-finger domains.