Literature DB >> 17664067

Membrane permeable esterase-activated fluorescent imaging probe.

Youngmi Kim1, Yongdoo Choi, Ralph Weissleder, Ching-Hsuan Tung.   

Abstract

An esterase-triggered probe 2 derived from a cyanine-based pH sensitive dye was developed for cell labeling. Permeation of probe 2 into cells and subsequent hydrolytic activation by cellular esterases result in a bright fluorescent intracellular signal.

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Year:  2007        PMID： 17664067      PMCID： PMC1995663          DOI： 10.1016/j.bmcl.2007.07.026

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  12 in total

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