Literature DB >> 17657909

NMR-based screening: a powerful tool in fragment-based drug discovery.

Jochen Klages1, Murray Coles, Horst Kessler.   

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Year:  2007        PMID： 17657909     DOI： 10.1039/b709658p

Source DB:  PubMed          Journal:  Analyst        ISSN： 0003-2654            Impact factor:   4.616


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  14 in total

1.  NMR-based exploration of the acceptor binding site of human blood group B galactosyltransferase with molecular fragments.

Authors:  Christoph Rademacher; Jens Landström; Nora Sindhuwinata; Monica M Palcic; Göran Widmalm; Thomas Peters
Journal:  Glycoconj J       Date:  2010-03-09       Impact factor: 2.916

Review 2.  Perspectives on NMR in drug discovery: a technique comes of age.

Authors:  Maurizio Pellecchia; Ivano Bertini; David Cowburn; Claudio Dalvit; Ernest Giralt; Wolfgang Jahnke; Thomas L James; Steve W Homans; Horst Kessler; Claudio Luchinat; Bernd Meyer; Hartmut Oschkinat; Jeff Peng; Harald Schwalbe; Gregg Siegal
Journal:  Nat Rev Drug Discov       Date:  2008-09       Impact factor: 84.694

3.  Formation of the RFX gene regulatory complex induces folding of the interaction domain of RFXAP.

Authors:  LaTese Briggs; Kholiswa Laird; Jeremy M Boss; Colin W Garvie
Journal:  Proteins       Date:  2009-08-15

Review 4.  Fragment-based drug discovery using NMR spectroscopy.

Authors:  Mary J Harner; Andreas O Frank; Stephen W Fesik
Journal:  J Biomol NMR       Date:  2013-05-18       Impact factor: 2.835

5.  Development and NMR validation of minimal pharmacophore hypotheses for the generation of fragment libraries enriched in heparanase inhibitors.

Authors:  Rafael Gozalbes; Silvia Mosulén; Rodrigo J Carbajo; Antonio Pineda-Lucena
Journal:  J Comput Aided Mol Des       Date:  2009-05-07       Impact factor: 3.686

6.  Improved synthesis of polyfluorinated L-lysine for 19F NMR-based screening.

Authors:  Beatrice Malgesini; Eduard Felder; Nicola Mongelli; Gianluca Papeo
Journal:  Mol Divers       Date:  2008-11-22       Impact factor: 2.943

Review 7.  Recent contributions of structure-based drug design to the development of antibacterial compounds.

Authors:  Bart L Staker; Garry W Buchko; Peter J Myler
Journal:  Curr Opin Microbiol       Date:  2015-10       Impact factor: 7.934

8.  Perspectives of biomolecular NMR in drug discovery: the blessing and curse of versatility.

Authors:  Wolfgang Jahnke
Journal:  J Biomol NMR       Date:  2007-08-15       Impact factor: 2.582

9.  Protein-Templated Formation of an Inhibitor of the Blood Coagulation Factor Xa through a Background-Free Amidation Reaction.

Authors:  Mike Jaegle; Torsten Steinmetzer; Jörg Rademann
Journal:  Angew Chem Int Ed Engl       Date:  2017-02-15       Impact factor: 15.336

Review 10.  Solution NMR Spectroscopy in Target-Based Drug Discovery.

Authors:  Yan Li; Congbao Kang
Journal:  Molecules       Date:  2017-08-23       Impact factor: 4.411
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