Literature DB >> 19031002

Improved synthesis of polyfluorinated L-lysine for 19F NMR-based screening.

Beatrice Malgesini1, Eduard Felder, Nicola Mongelli, Gianluca Papeo.   

Abstract

Polyfluorinated N-alpha-Fmoc-is an element of-Boc-L-lysine represents the best-in-class among a set of polyfluorinated amino acids (PFAs) which are useful tools for (19)F NMR-Based Screening. In this communication, optimized reaction conditions that allowed for the multi-gram preparation of this unnatural amino acid are reported.

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Year:  2008        PMID： 19031002     DOI： 10.1007/s11030-008-9097-5

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  10 in total

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