Literature DB >> 17644583

SbcCD regulation and localization in Escherichia coli.

Elise Darmon1, Manuel A Lopez-Vernaza, Anne C Helness, Amanda Borking, Emily Wilson, Zubin Thacker, Laura Wardrope, David R F Leach.   

Abstract

The SbcCD complex and its homologues play important roles in DNA repair and in the maintenance of genome stability. In Escherichia coli, the in vitro functions of SbcCD have been well characterized, but its exact cellular role remains elusive. This work investigates the regulation of the sbcDC operon and the cellular localization of the SbcC and SbcD proteins. Transcription of the sbcDC operon is shown to be dependent on starvation and RpoS protein. Overexpressed SbcC protein forms foci that colocalize with the replication factory, while overexpressed SbcD protein is distributed through the cytoplasm.

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Year:  2007        PMID: 17644583      PMCID: PMC2045166          DOI: 10.1128/JB.00489-07

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  29 in total

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  9 in total

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5.  The DNA Exonucleases of Escherichia coli.

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6.  Time-course analysis of the Shewanella amazonensis SB2B proteome in response to sodium chloride shock.

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  9 in total

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