| Literature DB >> 17603102 |
Abstract
Cell-specific promoters allow only spatial control of transgene expression in Caenorhabditis elegans. We describe a method, using cell-specific rescue of heat-shock factor-1 (hsf-1) mutants, that allows spatial and temporal regulation of transgene expression. We demonstrate the utility of this method for timed reporter gene expression and for temporal studies of gene function.Entities:
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Year: 2007 PMID: 17603102 PMCID: PMC1950662 DOI: 10.1534/genetics.107.074369
Source DB: PubMed Journal: Genetics ISSN: 0016-6731 Impact factor: 4.562