Literature DB >> 17597420

Question 8: bridging the gap between in silico and in vitro approaches to minimal cells.

Fabio Mavelli1, Kepa Ruiz-Mirazo.   

Abstract

In this short paper we argue for the relevance and value of theoretical models in the field of origins of life, but also claim that both theoreticians and experimentalists should make an effort to come together and interact more closely to obtain more fruitful and significant results. As an example, we present our own modeling approach to protocell dynamics, including some simulation results, to show that it is possible to develop computational tools that start bridging that traditional gap between theory and experiments.

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Year:  2007        PMID: 17597420     DOI: 10.1007/s11084-007-9085-2

Source DB:  PubMed          Journal:  Orig Life Evol Biosph        ISSN: 0169-6149            Impact factor:   1.950


  12 in total

Review 1.  Artificial cells: prospects for biotechnology.

Authors:  Andrew Pohorille; David Deamer
Journal:  Trends Biotechnol       Date:  2002-03       Impact factor: 19.536

2.  Organization of chemical reactions into dividing and metabolizing units: the chemotons.

Authors:  T Gánti
Journal:  Biosystems       Date:  1975-07       Impact factor: 1.973

Review 3.  On the early evolutionary origin of biological periodicity.

Authors:  Tibor Gánti
Journal:  Cell Biol Int       Date:  2002       Impact factor: 3.612

4.  A Chemical Model of Homeostasis We would like to thank Dr. Sabrina Dallavalle, who under the direction of Prof. Stefano Colonna at the University of Milano carried out the first attempts to realize an autopoietic system, and F. Mayer for his help with gas chromatography analysis.

Authors:  Helmut H. Zepik; Eveline Blöchliger; Pier Luigi Luisi
Journal:  Angew Chem Int Ed Engl       Date:  2001-01-05       Impact factor: 15.336

Review 5.  Approaches to semi-synthetic minimal cells: a review.

Authors:  Pier Luigi Luisi; Francesca Ferri; Pasquale Stano
Journal:  Naturwissenschaften       Date:  2006-01

Review 6.  A giant step towards artificial life?

Authors:  David Deamer
Journal:  Trends Biotechnol       Date:  2005-07       Impact factor: 19.536

Review 7.  Synthetic protocell biology: from reproduction to computation.

Authors:  Ricard V Solé; Andreea Munteanu; Carlos Rodriguez-Caso; Javier Macía
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2007-10-29       Impact factor: 6.237

8.  Autocatalytic sets of proteins.

Authors:  S A Kauffman
Journal:  J Theor Biol       Date:  1986-03-07       Impact factor: 2.691

9.  Autopoiesis: the organization of living systems, its characterization and a model.

Authors:  F G Varela; H R Maturana; R Uribe
Journal:  Curr Mod Biol       Date:  1974-05

10.  The hypercycle. A principle of natural self-organization. Part A: Emergence of the hypercycle.

Authors:  M Eigen; P Schuster
Journal:  Naturwissenschaften       Date:  1977-11
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  1 in total

Review 1.  The role of natural selection in the origin of life.

Authors:  Iris Fry
Journal:  Orig Life Evol Biosph       Date:  2010-04-21       Impact factor: 1.950

  1 in total

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