Literature DB >> 17591914

Spatial luminance contrast sensitivity measured with transient VEP: comparison with psychophysics and evidence of multiple mechanisms.

Givago S Souza1, Bruno D Gomes, Cézar A Saito, Manoel da Silva Filho, Luiz Carlos L Silveira.   

Abstract

PURPOSE: To compare the spatial luminance contrast sensitivity function (CSF) obtained with transient visual evoked potentials (VEPs) with that obtained with psychophysical measurements.
METHODS: The stimuli consisted of horizontal luminance gratings. In the VEP experiments, 0.4, 0.8, 2, 4, 8, and 10 cpd of spatial frequency were used, at 1 Hz square-wave contrast-reversal mode. Eight to 10 Michelson contrasts were used at each spatial frequency. Contrast thresholds were estimated from extrapolation of contrast response functions. Psychophysical sensitivities were obtained with spatial gratings of 0.4, 0.8, 1, 2, 4, 6, 8, and 10 cpd and presented at 1 Hz square-wave contrast-reversal or stationary mode (dynamic and static presentation, respectively). CSF tuning was estimated by calculating the ratio between peak sensitivity and the sensitivity at 0.4 cpd.
RESULTS: In all subjects tested (n = 6), VEP contrast-response functions showed nonlinearities-namely, amplitude saturation and double-slope amplitude functions that occurred at low and medium-to-high spatial frequencies, respectively. Mean electrophysiological and psychophysical CSFs peaked at 2 cpd. CSF tuning for electrophysiology and dynamic and static psychophysics were, respectively, 1.08, 1.11, and 1.31. Correlation coefficients (r(2)) between electrophysiological CSF and dynamic or static psychophysical CSF were, respectively, 0.81 and 0.45.
CONCLUSIONS: Electrophysiological and psychophysical CSFs correlated more positively when temporal presentation was similar. Spatial frequencies higher than 2 cpd showed that at least two visual pathways sum their activities at high contrasts. At low contrast levels, the results suggest that the transient VEP is dominated by the magnocellular (M) pathway.

Mesh:

Year:  2007        PMID: 17591914     DOI: 10.1167/iovs.07-0018

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


  14 in total

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