OBJECTIVE: The aim of this study was to compare the accuracy of the CeVOX monitor measuring continuous central venous saturation (ScvO(2)) with laboratory blood gas oximetry under clinical circumstances. DESIGN: Prospective, multicentre, observational study. SETTING: Five adult general intensive care units. PATIENTS AND PARTICIPANTS: Fifty-three critically ill patients. INTERVENTIONS: The fibre-optic probe was inserted into an ordinary central venous catheter's distal lumen. Blood samples were taken from this line via a Y-adapter every 8 h and ScvO(2) was measured with a laboratory co-oximeter. Patients were observed for a maximum of 5 days. Results were compared using linear regression and the Bland and Altman plots. MEASUREMENTS AND RESULTS: The 526 matched pairs of ScvO(2) showed a significant correlation between the two methods (r = 0.79, p< 0.001). Bland-Altman plots showed an overall mean bias of -0.3% and moderate agreement (lower and upper levels of agreement: -13.2% and 12.5%). Correlation for the first time point, and for differences between the first two time points for each method revealed good correlation: (n = 53): r = 0.79, p< 0.001; (n = 50): r = 0.58, p< 0.001, respectively. CONCLUSION: These results in a heterogeneous group of critically ill patients show that continuous ScvO(2) monitoring by the CeVOX technology yielded results comparable with those obtained by laboratory co-oximetry and therefore can be relied on in everyday clinical practice.
OBJECTIVE: The aim of this study was to compare the accuracy of the CeVOX monitor measuring continuous central venous saturation (ScvO(2)) with laboratory blood gas oximetry under clinical circumstances. DESIGN: Prospective, multicentre, observational study. SETTING: Five adult general intensive care units. PATIENTS AND PARTICIPANTS: Fifty-three critically illpatients. INTERVENTIONS: The fibre-optic probe was inserted into an ordinary central venous catheter's distal lumen. Blood samples were taken from this line via a Y-adapter every 8 h and ScvO(2) was measured with a laboratory co-oximeter. Patients were observed for a maximum of 5 days. Results were compared using linear regression and the Bland and Altman plots. MEASUREMENTS AND RESULTS: The 526 matched pairs of ScvO(2) showed a significant correlation between the two methods (r = 0.79, p< 0.001). Bland-Altman plots showed an overall mean bias of -0.3% and moderate agreement (lower and upper levels of agreement: -13.2% and 12.5%). Correlation for the first time point, and for differences between the first two time points for each method revealed good correlation: (n = 53): r = 0.79, p< 0.001; (n = 50): r = 0.58, p< 0.001, respectively. CONCLUSION: These results in a heterogeneous group of critically illpatients show that continuous ScvO(2) monitoring by the CeVOX technology yielded results comparable with those obtained by laboratory co-oximetry and therefore can be relied on in everyday clinical practice.
Authors: J Y Lefrant; L Muller; P Bruelle; J L Pandolfi; J L'Hermite; P Peray; G Saïssi; J E de La Coussaye; J J Eledjam Journal: Crit Care Med Date: 2000-02 Impact factor: 7.598
Authors: C Ladakis; P Myrianthefs; A Karabinis; G Karatzas; T Dosios; G Fildissis; J Gogas; G Baltopoulos Journal: Respiration Date: 2001 Impact factor: 3.580
Authors: Massimo Antonelli; Elie Azoulay; Marc Bonten; Jean Chastre; Giuseppe Citerio; Giorgio Conti; Daniel De Backer; François Lemaire; Herwig Gerlach; Johan Groeneveld; Goran Hedenstierna; Duncan Macrae; Jordi Mancebo; Salvatore M Maggiore; Alexandre Mebazaa; Philipp Metnitz; Jerme Pugin; Jan Wernerman; Haibo Zhang Journal: Intensive Care Med Date: 2008-01-31 Impact factor: 17.440
Authors: Werner Baulig; Alexander Dullenkopf; Andreas Kobler; Barbara Baulig; Hans Rudolf Roth; Edith R Schmid Journal: J Clin Monit Comput Date: 2008-04-29 Impact factor: 2.502
Authors: Alexander Herner; Bernhard Haller; Ulrich Mayr; Sebastian Rasch; Lea Offman; Roland Schmid; Wolfgang Huber Journal: PLoS One Date: 2018-04-17 Impact factor: 3.240