Literature DB >> 17572743

Improved rejection of multiply scattered photons in confocal microscopy using dual-axes architecture.

Larry K Wong1, Michael J Mandella, Gordon S Kino, Thomas D Wang.   

Abstract

We perform Monte Carlo simulations to show that the dual-axes (DA) confocal architecture has superior rejection of multiply scattered photons in tissue to that of single axis. As a result, the DA configuration provides improved signal-to-noise ratio and dynamic range, and thus is sensitive to ballistic photons from deeper within tissue, features that are particularly useful for performing vertical cross-sectional reflectance images in tissue.

Mesh：

Year:  2007        PMID： 17572743      PMCID： PMC2104523          DOI： 10.1364/ol.32.001674

Source DB:  PubMed          Journal:  Opt Lett        ISSN： 0146-9592            Impact factor:   3.776


  7 in total

1.  Dual-axis confocal microscope for high-resolution in vivo imaging.

Authors:  Thomas D Wang; Michael J Mandella; Christopher H Contag; Gordon S Kino
Journal:  Opt Lett       Date:  2003-03-15       Impact factor: 3.776

2.  Dual-axes confocal microscopy with post-objective scanning and low-coherence heterodyne detection.

Authors:  Thomas D Wang; Christopher H Contag; Michael J Mandella; Ning Y Chan; Gordon S Kino
Journal:  Opt Lett       Date:  2003-10-15       Impact factor: 3.776

3.  Clinical determination of tissue optical properties by endoscopic spatially resolved reflectometry.

Authors:  R Bays; G Wagnières; D Robert; D Braichotte; J F Savary; P Monnier; H van den Bergh
Journal:  Appl Opt       Date:  1996-04-01       Impact factor: 1.980

4.  Dual-axes confocal reflectance microscope for distinguishing colonic neoplasia.

Authors:  Jonathan T C Liu; Michael J Mandella; Shai Friedland; Roy Soetikno; James M Crawford; Christopher H Contag; Gordon S Kino; Thomas D Wang
Journal:  J Biomed Opt       Date:  2006 Sep-Oct       Impact factor: 3.170

5.  Three-dimensional miniature endoscopy.

Authors:  D Yelin; I Rizvi; W M White; J T Motz; T Hasan; B E Bouma; G J Tearney
Journal:  Nature       Date:  2006-10-19       Impact factor: 49.962

6.  Confocal microscope with large field and working distance.

Authors:  R H Webb; F Rogomentich
Journal:  Appl Opt       Date:  1999-08-01       Impact factor: 1.980

7.  Micromachined scanning confocal optical microscope.

Authors:  D L Dickensheets; G S Kino
Journal:  Opt Lett       Date:  1996-05-15       Impact factor: 3.776
  7 in total
  10 in total

1.  Micromirror-scanned dual-axis confocal microscope utilizing a gradient-index relay lens for image guidance during brain surgery.

Authors:  Jonathan T C Liu; Michael J Mandella; Nathan O Loewke; Henry Haeberle; Hyejun Ra; Wibool Piyawattanametha; Olav Solgaard; Gordon S Kino; Christopher H Contag
Journal:  J Biomed Opt       Date:  2010 Mar-Apr       Impact factor: 3.170

2.  Three-dimensional in vivo imaging by a handheld dual-axes confocal microscope.

Authors:  Hyejun Ra; Wibool Piyawattanametha; Michael J Mandella; Pei-Lin Hsiung; Jonathan Hardy; Thomas D Wang; Christopher H Contag; Gordon S Kino; Olav Solgaard
Journal:  Opt Express       Date:  2008-05-12       Impact factor: 3.894

3.  Optimizing the performance of dual-axis confocal microscopes via Monte-Carlo scattering simulations and diffraction theory.

Authors:  Ye Chen; Jonathan T C Liu
Journal:  J Biomed Opt       Date:  2013-06       Impact factor: 3.170

4.  Dual-axis optical coherence tomography for deep tissue imaging.

Authors:  Yang Zhao; Will J Eldridge; Jason R Maher; Sanghoon Kim; Michael Crose; Mohamed Ibrahim; Howard Levinson; Adam Wax
Journal:  Opt Lett       Date:  2017-06-15       Impact factor: 3.776

5.  Modulated-alignment dual-axis (MAD) confocal microscopy for deep optical sectioning in tissues.

Authors:  Steven Y Leigh; Ye Chen; Jonathan T C Liu
Journal:  Biomed Opt Express       Date:  2014-04-30       Impact factor: 3.732

Review 6.  Trends in fluorescence image-guided surgery for gliomas.

Authors:  Jonathan T C Liu; Daphne Meza; Nader Sanai
Journal:  Neurosurgery       Date:  2014-07       Impact factor: 4.654

7.  Assessing delivery and quantifying efficacy of small interfering ribonucleic acid therapeutics in the skin using a dual-axis confocal microscope.

Authors:  Hyejun Ra; Emilio Gonzalez-Gonzalez; Bryan R Smith; Sanjiv S Gambhir; Gordon S Kino; Olav Solgaard; Roger L Kaspar; Christopher H Contag
Journal:  J Biomed Opt       Date:  2010 May-Jun       Impact factor: 3.170

8.  Optical-sectioning microscopy of protoporphyrin IX fluorescence in human gliomas: standardization and quantitative comparison with histology.

Authors:  Linpeng Wei; Ye Chen; Chengbo Yin; Sabine Borwege; Nader Sanai; Jonathan T C Liu
Journal:  J Biomed Opt       Date:  2017-04-01       Impact factor: 3.170

9.  Targeted vertical cross-sectional imaging with handheld near-infrared dual axes confocal fluorescence endomicroscope.

Authors:  Zhen Qiu; Zhongyao Liu; Xiyu Duan; Supang Khondee; Bishnu Joshi; Michael J Mandella; Kenn Oldham; Katsuo Kurabayashi; Thomas D Wang
Journal:  Biomed Opt Express       Date:  2013-01-24       Impact factor: 3.732

10.  Review of advanced imaging techniques.

Authors:  Yu Chen; Chia-Pin Liang; Yang Liu; Andrew H Fischer; Anil V Parwani; Liron Pantanowitz
Journal:  J Pathol Inform       Date:  2012-05-28
  10 in total

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